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Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma.
Torrini C, Nguyen TTT, Shu C, Mela A, Humala N, Mahajan A, Seeley EH, Zhang G, Westhoff MA, Karpel-Massler G, Bruce JN, Canoll P, Siegelin MD. Torrini C, et al. Among authors: shu c. Mol Cell. 2022 Aug 18;82(16):3061-3076.e6. doi: 10.1016/j.molcel.2022.06.030. Epub 2022 Aug 9. Mol Cell. 2022. PMID: 35948010 Free PMC article.
PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma.
Karpel-Massler G, Pareja F, Aimé P, Shu C, Chau L, Westhoff MA, Halatsch ME, Crary JF, Canoll P, Siegelin MD. Karpel-Massler G, et al. Among authors: shu c. PLoS One. 2014 Dec 22;9(12):e114583. doi: 10.1371/journal.pone.0114583. eCollection 2014. PLoS One. 2014. PMID: 25531448 Free PMC article.
A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers.
Karpel-Massler G, Horst BA, Shu C, Chau L, Tsujiuchi T, Bruce JN, Canoll P, Greene LA, Angelastro JM, Siegelin MD. Karpel-Massler G, et al. Among authors: shu c. Clin Cancer Res. 2016 Sep 15;22(18):4698-711. doi: 10.1158/1078-0432.CCR-15-2827. Epub 2016 Apr 28. Clin Cancer Res. 2016. PMID: 27126996 Free PMC article.
1,990 results