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Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.
Saltz J, Gupta R, Hou L, Kurc T, Singh P, Nguyen V, Samaras D, Shroyer KR, Zhao T, Batiste R, Van Arnam J; Cancer Genome Atlas Research Network; Shmulevich I, Rao AUK, Lazar AJ, Sharma A, Thorsson V. Saltz J, et al. Among authors: shmulevich i. Cell Rep. 2018 Apr 3;23(1):181-193.e7. doi: 10.1016/j.celrep.2018.03.086. Cell Rep. 2018. PMID: 29617659 Free PMC article.
Exploring approaches for predictive cancer patient digital twins: Opportunities for collaboration and innovation.
Stahlberg EA, Abdel-Rahman M, Aguilar B, Asadpoure A, Beckman RA, Borkon LL, Bryan JN, Cebulla CM, Chang YH, Chatterjee A, Deng J, Dolatshahi S, Gevaert O, Greenspan EJ, Hao W, Hernandez-Boussard T, Jackson PR, Kuijjer M, Lee A, Macklin P, Madhavan S, McCoy MD, Mohammad Mirzaei N, Razzaghi T, Rocha HL, Shahriyari L, Shmulevich I, Stover DG, Sun Y, Syeda-Mahmood T, Wang J, Wang Q, Zervantonakis I. Stahlberg EA, et al. Among authors: shmulevich i. Front Digit Health. 2022 Oct 6;4:1007784. doi: 10.3389/fdgth.2022.1007784. eCollection 2022. Front Digit Health. 2022. PMID: 36274654 Free PMC article.
Digital twins in medicine.
Laubenbacher R, Mehrad B, Shmulevich I, Trayanova N. Laubenbacher R, et al. Among authors: shmulevich i. Nat Comput Sci. 2024 Mar;4(3):184-191. doi: 10.1038/s43588-024-00607-6. Epub 2024 Mar 26. Nat Comput Sci. 2024. PMID: 38532133 Review.
A framework towards digital twins for type 2 diabetes.
Zhang Y, Qin G, Aguilar B, Rappaport N, Yurkovich JT, Pflieger L, Huang S, Hood L, Shmulevich I. Zhang Y, et al. Among authors: shmulevich i. Front Digit Health. 2024 Jan 26;6:1336050. doi: 10.3389/fdgth.2024.1336050. eCollection 2024. Front Digit Health. 2024. PMID: 38343907 Free PMC article.
Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia.
Qin G, Dai J, Chien S, Martins TJ, Loera B, Nguyen QH, Oakes ML, Tercan B, Aguilar B, Hagen L, McCune J, Gelinas R, Monnat RJ Jr, Shmulevich I, Becker PS. Qin G, et al. Among authors: shmulevich i. Clin Cancer Res. 2024 Apr 15:OF1-OF13. doi: 10.1158/1078-0432.CCR-23-1674. Online ahead of print. Clin Cancer Res. 2024. PMID: 38619278
Toward mechanistic medical digital twins: some use cases in immunology.
Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca LL, Glazier J, Helikar T, Jett-Tilton M, Kirschner D, Macklin P, Mehrad B, Moore B, Pasour V, Shmulevich I, Smith A, Voigt I, Yankeelov TE, Ziemssen T. Laubenbacher R, et al. Among authors: shmulevich i. Front Digit Health. 2024 Mar 7;6:1349595. doi: 10.3389/fdgth.2024.1349595. eCollection 2024. Front Digit Health. 2024. PMID: 38515550 Free PMC article. Review.
Forum on immune digital twins: a meeting report.
Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca LL, Glazier J, Helikar T, Jett-Tilton M, Kirschner D, Macklin P, Mehrad B, Moore B, Pasour V, Shmulevich I, Smith A, Voigt I, Yankeelov TE, Ziemssen T. Laubenbacher R, et al. Among authors: shmulevich i. NPJ Syst Biol Appl. 2024 Feb 16;10(1):19. doi: 10.1038/s41540-024-00345-5. NPJ Syst Biol Appl. 2024. PMID: 38365857 Free PMC article. Review.
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F, Demeulemeester J, Santamarina M, Ju YS, Temes J, Garcia-Souto D, Detering H, Li Y, Rodriguez-Castro J, Dueso-Barroso A, Bruzos AL, Dentro SC, Blanco MG, Contino G, Ardeljan D, Tojo M, Roberts ND, Zumalave S, Edwards PA, Weischenfeldt J, Puiggròs M, Chong Z, Chen K, Lee EA, Wala JA, Raine KM, Butler A, Waszak SM, Navarro FCP, Schumacher SE, Monlong J, Maura F, Bolli N, Bourque G, Gerstein M, Park PJ, Wedge DC, Beroukhim R, Torrents D, Korbel JO, Martincorena I, Fitzgerald RC, Van Loo P, Kazazian HH, Burns KH; PCAWG Structural Variation Working Group; Campbell PJ, Tubio JMC; PCAWG Consortium. Rodriguez-Martin B, et al. Nat Genet. 2023 Jun;55(6):1080. doi: 10.1038/s41588-023-01319-9. Nat Genet. 2023. PMID: 36944736 Free PMC article. No abstract available.
243 results