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Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease.
Xu X, Jin K, Bais AS, Zhu W, Yagi H, Feinstein TN, Nguyen PK, Criscione JD, Liu X, Beutner G, Karunakaran KB, Rao KS, He H, Adams P, Kuo CK, Kostka D, Pryhuber GS, Shiva S, Ganapathiraju MK, Porter GA Jr, Lin JI, Aronow B, Lo CW. Xu X, et al. Among authors: shiva s. Cell Stem Cell. 2022 May 5;29(5):840-855.e7. doi: 10.1016/j.stem.2022.03.003. Epub 2022 Apr 7. Cell Stem Cell. 2022. PMID: 35395180 Free PMC article.
Tead1 is essential for mitochondrial function in cardiomyocytes.
Liu R, Jagannathan R, Sun L, Li F, Yang P, Lee J, Negi V, Perez-Garcia EM, Shiva S, Yechoor VK, Moulik M. Liu R, et al. Among authors: shiva s. Am J Physiol Heart Circ Physiol. 2020 Jul 1;319(1):H89-H99. doi: 10.1152/ajpheart.00732.2019. Epub 2020 Jun 5. Am J Physiol Heart Circ Physiol. 2020. PMID: 32502376 Free PMC article.
Chronic hypoxia induces right heart failure in caveolin-1-/- mice.
Cruz JA, Bauer EM, Rodriguez AI, Gangopadhyay A, Zeineh NS, Wang Y, Shiva S, Champion HC, Bauer PM. Cruz JA, et al. Among authors: shiva s. Am J Physiol Heart Circ Physiol. 2012 Jun 15;302(12):H2518-27. doi: 10.1152/ajpheart.01140.2011. Epub 2012 Apr 13. Am J Physiol Heart Circ Physiol. 2012. PMID: 22505641 Free PMC article.
273 results