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Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation.
Dalton WB, Helmenstine E, Walsh N, Gondek LP, Kelkar DS, Read A, Natrajan R, Christenson ES, Roman B, Das S, Zhao L, Leone RD, Shinn D, Groginski T, Madugundu AK, Patil A, Zabransky DJ, Medford A, Lee J, Cole AJ, Rosen M, Thakar M, Ambinder A, Donaldson J, DeZern AE, Cravero K, Chu D, Madero-Marroquin R, Pandey A, Hurley PJ, Lauring J, Park BH. Dalton WB, et al. Among authors: shinn d. J Clin Invest. 2019 Aug 8;129(11):4708-4723. doi: 10.1172/JCI125022. J Clin Invest. 2019. PMID: 31393856 Free PMC article.
NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model.
Cravero K, Pantone MV, Shin DH, Bergman R, Cochran R, Chu D, Zabransky DJ, Karthikeyan S, Waters IG, Hunter N, Rosen DM, Kyker-Snowman K, Dalton WB, Button B, Shinn D, Wong HY, Donaldson J, Hurley PJ, Croessmann S, Park BH. Cravero K, et al. Among authors: shinn d. Oncotarget. 2022 Feb 16;13:373-386. doi: 10.18632/oncotarget.28200. eCollection 2022. Oncotarget. 2022. PMID: 35186194 Free PMC article.
Detection fidelity of AR mutations in plasma derived cell-free DNA.
Goldstein A, Toro PV, Lee J, Silberstein JL, Nakazawa M, Waters I, Cravero K, Chu D, Cochran RL, Kim M, Shinn D, Torquato S, Hughes RM, Pallavajjala A, Carducci MA, Paller CJ, Denmeade SR, Kressel B, Trock BJ, Eisenberger MA, Antonarakis ES, Park BH, Hurley PJ. Goldstein A, et al. Among authors: shinn d. Oncotarget. 2017 Feb 28;8(9):15651-15662. doi: 10.18632/oncotarget.14926. Oncotarget. 2017. PMID: 28152506 Free PMC article.
Genetic Alterations Detected in Cell-Free DNA Are Associated With Enzalutamide and Abiraterone Resistance in Castration-Resistant Prostate Cancer.
Torquato S, Pallavajjala A, Goldstein A, Toro PV, Silberstein JL, Lee J, Nakazawa M, Waters I, Chu D, Shinn D, Groginski T, Hughes RM, Simons BW, Khan H, Feng Z, Carducci MA, Paller CJ, Denmeade SR, Kressel B, Eisenberger MA, Antonarakis ES, Trock BJ, Park BH, Hurley PJ. Torquato S, et al. Among authors: shinn d. JCO Precis Oncol. 2019;3:PO.18.00227. doi: 10.1200/PO.18.00227. Epub 2019 Apr 3. JCO Precis Oncol. 2019. PMID: 31131348 Free PMC article.
Improved Graft Function following Desensitization of Anti-AT1R and Autoantibodies in a Heart Transplant Recipient Negative for Donor-Specific Antibodies with Antibody-Mediated Rejection: A Case Report.
Jung R, Ly K, Taniguchi M, Arriola AG, Gravante C, Shinn D, Mathew L, Hamad E, Geier S, Liacini A. Jung R, et al. Among authors: shinn d. Int J Mol Sci. 2024 Feb 12;25(4):2218. doi: 10.3390/ijms25042218. Int J Mol Sci. 2024. PMID: 38396895 Free PMC article.
51 results