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An App knock-in rat model for Alzheimer's disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments.
Pang K, Jiang R, Zhang W, Yang Z, Li LL, Shimozawa M, Tambaro S, Mayer J, Zhang B, Li M, Wang J, Liu H, Yang A, Chen X, Liu J, Winblad B, Han H, Jiang T, Wang W, Nilsson P, Guo W, Lu B. Pang K, et al. Among authors: shimozawa m. Cell Res. 2022 Feb;32(2):157-175. doi: 10.1038/s41422-021-00582-x. Epub 2021 Nov 17. Cell Res. 2022. PMID: 34789895 Free PMC article.
Benzimidazole-based fluorophores for the detection of amyloid fibrils with higher sensitivity than Thioflavin-T.
Pravin N, Kumar R, Tripathi S, Kumar P, Mohite GM, Navalkar A, Panigrahi R, Singh N, Gadhe LG, Manchanda S, Shimozawa M, Nilsson P, Johansson J, Kumar A, Maji SK, Shanmugam M. Pravin N, et al. Among authors: shimozawa m. J Neurochem. 2021 Mar;156(6):1003-1019. doi: 10.1111/jnc.15138. Epub 2020 Sep 9. J Neurochem. 2021. PMID: 32750740 Free article.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: shimozawa m. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
Autophagy Impairment in App Knock-in Alzheimer's Model Mice.
Jiang R, Shimozawa M, Mayer J, Tambaro S, Kumar R, Abelein A, Winblad B, Bogdanovic N, Nilsson P. Jiang R, et al. Among authors: shimozawa m. Front Aging Neurosci. 2022 May 19;14:878303. doi: 10.3389/fnagi.2022.878303. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35663567 Free PMC article.
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling.
Naia L, Pinho CM, Dentoni G, Liu J, Leal NS, Ferreira DMS, Schreiner B, Filadi R, Fão L, Connolly NMC, Forsell P, Nordvall G, Shimozawa M, Greotti E, Basso E, Theurey P, Gioran A, Joselin A, Arsenian-Henriksson M, Nilsson P, Rego AC, Ruas JL, Park D, Bano D, Pizzo P, Prehn JHM, Ankarcrona M. Naia L, et al. Among authors: shimozawa m. BMC Biol. 2021 Mar 24;19(1):57. doi: 10.1186/s12915-021-00979-5. BMC Biol. 2021. PMID: 33761951 Free PMC article.
Plasma membrane phosphatidylinositol (4,5)-bisphosphate is critical for determination of epithelial characteristics.
Kanemaru K, Shimozawa M, Kitamata M, Furuishi R, Kayano H, Sukawa Y, Chiba Y, Fukuyama T, Hasegawa J, Nakanishi H, Kishimoto T, Tsujita K, Tanaka K, Itoh T, Sasaki J, Sasaki T, Fukami K, Nakamura Y. Kanemaru K, et al. Among authors: shimozawa m. Nat Commun. 2022 May 9;13(1):2347. doi: 10.1038/s41467-022-30061-9. Nat Commun. 2022. PMID: 35534464 Free PMC article.
A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme.
Nakahara M, Shimozawa M, Nakamura Y, Irino Y, Morita M, Kudo Y, Fukami K. Nakahara M, et al. Among authors: shimozawa m. J Biol Chem. 2005 Aug 12;280(32):29128-34. doi: 10.1074/jbc.M503817200. Epub 2005 May 17. J Biol Chem. 2005. PMID: 15899900 Free article.
48 results