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A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.
Tsuburaya N, Homma K, Higuchi T, Balia A, Yamakoshi H, Shibata N, Nakamura S, Nakagawa H, Ikeda SI, Umezawa N, Kato N, Yokoshima S, Shibuya M, Shimonishi M, Kojima H, Okabe T, Nagano T, Naguro I, Imamura K, Inoue H, Fujisawa T, Ichijo H. Tsuburaya N, et al. Among authors: shimonishi m. Nat Commun. 2018 Jul 10;9(1):2668. doi: 10.1038/s41467-018-05127-2. Nat Commun. 2018. PMID: 29991716 Free PMC article.
Gliotoxin suppresses NF-κB activation by selectively inhibiting linear ubiquitin chain assembly complex (LUBAC).
Sakamoto H, Egashira S, Saito N, Kirisako T, Miller S, Sasaki Y, Matsumoto T, Shimonishi M, Komatsu T, Terai T, Ueno T, Hanaoka K, Kojima H, Okabe T, Wakatsuki S, Iwai K, Nagano T. Sakamoto H, et al. Among authors: shimonishi m. ACS Chem Biol. 2015 Mar 20;10(3):675-81. doi: 10.1021/cb500653y. Epub 2014 Dec 17. ACS Chem Biol. 2015. PMID: 25494483
[Prostanoid synthases].
Shimonishi M, Tanabe T. Shimonishi M, et al. Tanpakushitsu Kakusan Koso. 1999 Jun;44(8 Suppl):1097-103. Tanpakushitsu Kakusan Koso. 1999. PMID: 10396989 Review. Japanese. No abstract available.
Prostacyclin-dependent apoptosis mediated by PPAR delta.
Hatae T, Wada M, Yokoyama C, Shimonishi M, Tanabe T. Hatae T, et al. Among authors: shimonishi m. J Biol Chem. 2001 Dec 7;276(49):46260-7. doi: 10.1074/jbc.M107180200. J Biol Chem. 2001. PMID: 11551955 Free article.
37 results