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IL-7 and CCL19-secreting CAR-T cell therapy for tumors with positive glypican-3 or mesothelin.
Pang N, Shi J, Qin L, Chen A, Tang Y, Yang H, Huang Y, Wu Q, Li X, He B, Li T, Liang B, Zhang J, Cao B, Liu M, Feng Y, Ye X, Chen X, Wang L, Tian Y, Li H, Li J, Hu H, He J, Hu Y, Zhi C, Tang Z, Gong Y, Xu F, Xu L, Fan W, Zhao M, Chen D, Lian H, Yang L, Li P, Zhang Z. Pang N, et al. Among authors: shi j. J Hematol Oncol. 2021 Jul 29;14(1):118. doi: 10.1186/s13045-021-01128-9. J Hematol Oncol. 2021. PMID: 34325726 Free PMC article. Clinical Trial.
Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer.
Lv J, Zhao R, Wu D, Zheng D, Wu Z, Shi J, Wei X, Wu Q, Long Y, Lin S, Wang S, Wang Z, Li Y, Chen Y, He Q, Chen S, Yao H, Liu Z, Tang Z, Yao Y, Pei D, Liu P, Zhang X, Zhang Z, Cui S, Chen R, Li P. Lv J, et al. Among authors: shi j. J Hematol Oncol. 2019 Feb 18;12(1):18. doi: 10.1186/s13045-019-0704-y. J Hematol Oncol. 2019. PMID: 30777106 Free PMC article.
Human induced-T-to-natural killer cells have potent anti-tumour activities.
Jiang Z, Qin L, Tang Y, Liao R, Shi J, He B, Li S, Zheng D, Cui Y, Wu Q, Long Y, Yao Y, Wei Z, Hong Q, Wu Y, Mai Y, Gou S, Li X, Weinkove R, Norton S, Luo W, Feng W, Zhou H, Liu Q, Chen J, Lai L, Chen X, Pei D, Graf T, Liu X, Li Y, Liu P, Zhang Z, Li P. Jiang Z, et al. Among authors: shi j. Biomark Res. 2022 Mar 24;10(1):13. doi: 10.1186/s40364-022-00358-4. Biomark Res. 2022. PMID: 35331335 Free PMC article.
DAP10 integration in CAR-T cells enhances the killing of heterogeneous tumors by harnessing endogenous NKG2D.
Li S, Zhao R, Zheng D, Qin L, Cui Y, Li Y, Jiang Z, Zhong M, Shi J, Li M, Wang X, Tang Z, Wu Q, Long Y, Hu D, Wang S, Yao Y, Liu S, Yang LH, Zhang Z, Tang Q, Liu P, Li Y, Li P. Li S, et al. Among authors: shi j. Mol Ther Oncolytics. 2022 Jun 6;26:15-26. doi: 10.1016/j.omto.2022.06.003. eCollection 2022 Sep 15. Mol Ther Oncolytics. 2022. PMID: 35784403 Free PMC article.
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