Shi H - Search Results

1

Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia.

Gocho Y, Liu J, Hu J, Yang W, Dharia NV, Zhang J, Shi H, Du G, John A, Lin TN, Hunt J, Huang X, Ju B, Rowland L, Shi L, Maxwell D, Smart B, Crews KR, Yang W, Hagiwara K, Zhang Y, Roberts K, Wang H, Jabbour E, Stock W, Eisfelder B, Paietta E, Newman S, Roti G, Litzow M, Easton J, Zhang J, Peng J, Chi H, Pounds S, Relling MV, Inaba H, Zhu X, Kornblau S, Pui CH, Konopleva M, Teachey D, Mullighan CG, Stegmaier K, Evans WE, Yu J, Yang JJ. Gocho Y, et al. Among authors: shi l, shi h. Nat Cancer. 2021 Mar;2(3):284-299. doi: 10.1038/s43018-020-00167-4. Epub 2021 Jan 21. Nat Cancer. 2021. PMID: 34151288 Free PMC article.

2

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

Li J, Du X, Shi H, Deng K, Chi H, Tao W. Li J, et al. Among authors: shi h. J Biol Chem. 2015 Dec 25;290(52):30762-70. doi: 10.1074/jbc.M115.668442. Epub 2015 Nov 3. J Biol Chem. 2015. PMID: 26538561 Free PMC article.

3

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H. Zeng H, et al. Among authors: shi h. Sci Adv. 2018 Jan 31;4(1):eaar5701. doi: 10.1126/sciadv.aar5701. eCollection 2018 Jan. Sci Adv. 2018. PMID: 29399633 Free PMC article.

4

Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.

Shi H, Liu C, Tan H, Li Y, Nguyen TM, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, Feng Y, Peng J, Tao W, Chi H. Shi H, et al. Immunity. 2018 Nov 20;49(5):899-914.e6. doi: 10.1016/j.immuni.2018.10.010. Epub 2018 Nov 6. Immunity. 2018. PMID: 30413360 Free PMC article.

5

Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.

Shi H, Chapman NM, Wen J, Guy C, Long L, Dhungana Y, Rankin S, Pelletier S, Vogel P, Wang H, Peng J, Guan KL, Chi H. Shi H, et al. Immunity. 2019 Dec 17;51(6):1012-1027.e7. doi: 10.1016/j.immuni.2019.10.001. Epub 2019 Oct 24. Immunity. 2019. PMID: 31668641 Free PMC article.

6

Metabolic Control of Treg Cell Stability, Plasticity, and Tissue-Specific Heterogeneity.

Shi H, Chi H. Shi H, et al. Front Immunol. 2019 Dec 11;10:2716. doi: 10.3389/fimmu.2019.02716. eCollection 2019. Front Immunol. 2019. PMID: 31921097 Free PMC article. Review.

7

Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions.

Raynor JL, Liu C, Dhungana Y, Guy C, Chapman NM, Shi H, Neale G, Sesaki H, Chi H. Raynor JL, et al. Among authors: shi h. J Exp Med. 2020 Jun 1;217(6):e20191157. doi: 10.1084/jem.20191157. J Exp Med. 2020. PMID: 32289155 Free PMC article.

8

Lipid signalling enforces functional specialization of T_reg cells in tumours.

Lim SA, Wei J, Nguyen TM, Shi H, Su W, Palacios G, Dhungana Y, Chapman NM, Long L, Saravia J, Vogel P, Chi H. Lim SA, et al. Among authors: shi h. Nature. 2021 Mar;591(7849):306-311. doi: 10.1038/s41586-021-03235-6. Epub 2021 Feb 24. Nature. 2021. PMID: 33627871 Free PMC article.

9

In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8⁺ T cell fate decisions.

Huang H, Zhou P, Wei J, Long L, Shi H, Dhungana Y, Chapman NM, Fu G, Saravia J, Raynor JL, Liu S, Palacios G, Wang YD, Qian C, Yu J, Chi H. Huang H, et al. Among authors: shi h. Cell. 2021 Mar 4;184(5):1245-1261.e21. doi: 10.1016/j.cell.2021.02.021. Epub 2021 Feb 25. Cell. 2021. PMID: 33636132 Free PMC article.

10

Metabolic control of T_FH cells and humoral immunity by phosphatidylethanolamine.

Fu G, Guy CS, Chapman NM, Palacios G, Wei J, Zhou P, Long L, Wang YD, Qian C, Dhungana Y, Huang H, Kc A, Shi H, Rankin S, Brown SA, Johnson A, Wakefield R, Robinson CG, Liu X, Sheyn A, Yu J, Jackowski S, Chi H. Fu G, et al. Among authors: shi h. Nature. 2021 Jul;595(7869):724-729. doi: 10.1038/s41586-021-03692-z. Epub 2021 Jul 7. Nature. 2021. PMID: 34234346 Free PMC article.

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