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RIP3 deficiency alleviates liver fibrosis by inhibiting ROCK1-TLR4-NF-κB pathway in macrophages.
Wei S, Zhou H, Wang Q, Zhou S, Li C, Liu R, Qiu J, Shi C, Lu L. Wei S, et al. Among authors: shi c. FASEB J. 2019 Oct 1;33(10):11180-11193. doi: 10.1096/fj.201900752R. Epub 2019 Jul 11. FASEB J. 2019. PMID: 31295018
In conclusion, our findings suggest that RIP3 plays a crucial proinflammatory role in liver fibrosis by regulating the ROCK1-TLR4-NF-kappaB signaling pathway in macrophages and therefore may be a potential therapeutic target for immune-mediated liver fibrosis.-Wei, S., Zhou, H., …
In conclusion, our findings suggest that RIP3 plays a crucial proinflammatory role in liver fibrosis by regulating the ROCK1-TLR4-NF-kappaB …
7,668 results