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Biallelic mutations in RNA-binding protein ADAD2 cause spermiogenic failure and non-obstructive azoospermia in humans.
Shi B, Shah W, Liu L, Gong C, Zhou J, Abbas T, Ma H, Zhang H, Yang M, Zhang Y, Ullah N, Mahammad Z, Khan M, Murtaza G, Ali A, Khan R, Sha J, Yuan Y, Shi Q. Shi B, et al. Among authors: shi q. Hum Reprod Open. 2023 May 18;2023(3):hoad022. doi: 10.1093/hropen/hoad022. eCollection 2023. Hum Reprod Open. 2023. PMID: 37325547 Free PMC article.
MORC2B is essential for meiotic progression and fertility.
Shi B, Xue J, Zhou J, Kasowitz SD, Zhang Y, Liang G, Guan Y, Shi Q, Liu M, Sha J, Huang X, Wang PJ. Shi B, et al. Among authors: shi q. PLoS Genet. 2018 Jan 12;14(1):e1007175. doi: 10.1371/journal.pgen.1007175. eCollection 2018 Jan. PLoS Genet. 2018. PMID: 29329290 Free PMC article.
Dual functions for the ssDNA-binding protein RPA in meiotic recombination.
Shi B, Xue J, Yin H, Guo R, Luo M, Ye L, Shi Q, Huang X, Liu M, Sha J, Wang PJ. Shi B, et al. Among authors: shi q. PLoS Genet. 2019 Feb 4;15(2):e1007952. doi: 10.1371/journal.pgen.1007952. eCollection 2019 Feb. PLoS Genet. 2019. PMID: 30716097 Free PMC article.
RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes.
Ma H, Li T, Xie X, Jiang L, Ye J, Gong C, Jiang H, Fan S, Zhang H, Shi B, Zhang B, Jiang X, Li Y, Zhou J, Xu J, Zhang X, Hou X, Yin H, Zhang Y, Shi Q. Ma H, et al. Among authors: shi q, shi b. Sci Adv. 2022 Jan 14;8(2):eabk1789. doi: 10.1126/sciadv.abk1789. Epub 2022 Jan 12. Sci Adv. 2022. PMID: 35020426 Free PMC article.
Biallelic HFM1 variants cause non-obstructive azoospermia with meiotic arrest in humans by impairing crossover formation to varying degrees.
Xie X, Murtaza G, Li Y, Zhou J, Ye J, Khan R, Jiang L, Khan I, Zubair M, Yin H, Jiang H, Liu W, Shi B, Hou X, Gong C, Fan S, Wang Y, Jiang X, Zhang Y, Zhang H, Ma H, Shi Q. Xie X, et al. Among authors: shi q, shi b. Hum Reprod. 2022 Jun 30;37(7):1664-1677. doi: 10.1093/humrep/deac092. Hum Reprod. 2022. PMID: 35526155
A homozygous KASH5 frameshift mutation causes diminished ovarian reserve, recurrent miscarriage, and non-obstructive azoospermia in humans.
Hou X, Zeb A, Dil S, Zhou J, Zhang H, Shi B, Muhammad Z, Khan I, Zaman Q, Shah WA, Jiang X, Wu L, Ma H, Shi Q. Hou X, et al. Among authors: shi q, shi b. Front Endocrinol (Lausanne). 2023 Feb 14;14:1128362. doi: 10.3389/fendo.2023.1128362. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36864840 Free PMC article.
A novel recombination protein C12ORF40/REDIC1 is required for meiotic crossover formation.
Fan S, Wang Y, Jiang H, Jiang X, Zhou J, Jiao Y, Ye J, Xu Z, Wang Y, Xie X, Zhang H, Li Y, Liu W, Zhang X, Ma H, Shi B, Zhang Y, Zubair M, Shah W, Xu Z, Xu B, Shi Q. Fan S, et al. Among authors: shi q, shi b. Cell Discov. 2023 Aug 23;9(1):88. doi: 10.1038/s41421-023-00577-5. Cell Discov. 2023. PMID: 37612290 Free PMC article.
5,146 results