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Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis.
Miguel V, Tituaña J, Herrero JI, Herrero L, Serra D, Cuevas P, Barbas C, Puyol DR, Márquez-Expósito L, Ruiz-Ortega M, Castillo C, Sheng X, Susztak K, Ruiz-Canela M, Salas-Salvadó J, González MAM, Ortega S, Ramos R, Lamas S. Miguel V, et al. Among authors: sheng x. J Clin Invest. 2021 Mar 1;131(5):e140695. doi: 10.1172/JCI140695. J Clin Invest. 2021. PMID: 33465052 Free PMC article.
Functional methylome analysis of human diabetic kidney disease.
Park J, Guan Y, Sheng X, Gluck C, Seasock MJ, Hakimi AA, Qiu C, Pullman J, Verma A, Li H, Palmer M, Susztak K. Park J, et al. Among authors: sheng x. JCI Insight. 2019 Jun 6;4(11):e128886. doi: 10.1172/jci.insight.128886. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167971 Free PMC article.
The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation.
Dhillon P, Park J, Hurtado Del Pozo C, Li L, Doke T, Huang S, Zhao J, Kang HM, Shrestra R, Balzer MS, Chatterjee S, Prado P, Han SY, Liu H, Sheng X, Dierickx P, Batmanov K, Romero JP, Prósper F, Li M, Pei L, Kim J, Montserrat N, Susztak K. Dhillon P, et al. Among authors: sheng x. Cell Metab. 2021 Feb 2;33(2):379-394.e8. doi: 10.1016/j.cmet.2020.11.011. Epub 2020 Dec 9. Cell Metab. 2021. PMID: 33301705 Free PMC article.
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.
Sheng X, Guan Y, Ma Z, Wu J, Liu H, Qiu C, Vitale S, Miao Z, Seasock MJ, Palmer M, Shin MK, Duffin KL, Pullen SS, Edwards TL, Hellwege JN, Hung AM, Li M, Voight BF, Coffman TM, Brown CD, Susztak K. Sheng X, et al. Nat Genet. 2021 Sep;53(9):1322-1333. doi: 10.1038/s41588-021-00909-9. Epub 2021 Aug 12. Nat Genet. 2021. PMID: 34385711 Free PMC article.
The key role of NLRP3 and STING in APOL1-associated podocytopathy.
Wu J, Raman A, Coffey NJ, Sheng X, Wahba J, Seasock MJ, Ma Z, Beckerman P, Laczkó D, Palmer MB, Kopp JB, Kuo JJ, Pullen SS, Boustany-Kari CM, Linkermann A, Susztak K. Wu J, et al. Among authors: sheng x. J Clin Invest. 2021 Oct 15;131(20):e136329. doi: 10.1172/JCI136329. J Clin Invest. 2021. PMID: 34651582 Free PMC article.
2,740 results