Shen Q - Search Results

1

Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes.

Shen Q, Cheng F, Song H, Lu W, Zhao J, An X, Liu M, Chen G, Zhao Z, Zhang J. Shen Q, et al. Am J Hum Genet. 2017 Jan 5;100(1):5-20. doi: 10.1016/j.ajhg.2016.09.020. Epub 2016 Dec 8. Am J Hum Genet. 2017. PMID: 27939638 Free PMC article.

2

Allosteric Methods and Their Applications: Facilitating the Discovery of Allosteric Drugs and the Investigation of Allosteric Mechanisms.

Lu S, Shen Q, Zhang J. Lu S, et al. Among authors: shen q. Acc Chem Res. 2019 Feb 19;52(2):492-500. doi: 10.1021/acs.accounts.8b00570. Epub 2019 Jan 28. Acc Chem Res. 2019. PMID: 30688063

3

Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs?

An X, Lu S, Song K, Shen Q, Huang M, Yao X, Liu H, Zhang J. An X, et al. Among authors: shen q. J Chem Inf Model. 2019 Jan 28;59(1):597-604. doi: 10.1021/acs.jcim.8b00735. Epub 2018 Dec 20. J Chem Inf Model. 2019. PMID: 30525607

4

AlloDriver: a method for the identification and analysis of cancer driver targets.

Song K, Li Q, Gao W, Lu S, Shen Q, Liu X, Wu Y, Wang B, Lin H, Chen G, Zhang J. Song K, et al. Among authors: shen q. Nucleic Acids Res. 2019 Jul 2;47(W1):W315-W321. doi: 10.1093/nar/gkz350. Nucleic Acids Res. 2019. PMID: 31069394 Free PMC article.

5

ASD v2.0: updated content and novel features focusing on allosteric regulation.

Huang Z, Mou L, Shen Q, Lu S, Li C, Liu X, Wang G, Li S, Geng L, Liu Y, Wu J, Chen G, Zhang J. Huang Z, et al. Among authors: shen q. Nucleic Acids Res. 2014 Jan;42(Database issue):D510-6. doi: 10.1093/nar/gkt1247. Epub 2013 Nov 28. Nucleic Acids Res. 2014. PMID: 24293647 Free PMC article.

6

ASD v3.0: unraveling allosteric regulation with structural mechanisms and biological networks.

Shen Q, Wang G, Li S, Liu X, Lu S, Chen Z, Song K, Yan J, Geng L, Huang Z, Huang W, Chen G, Zhang J. Shen Q, et al. Nucleic Acids Res. 2016 Jan 4;44(D1):D527-35. doi: 10.1093/nar/gkv902. Epub 2015 Sep 13. Nucleic Acids Res. 2016. PMID: 26365237 Free PMC article.

7

Improved Method for the Identification and Validation of Allosteric Sites.

Song K, Liu X, Huang W, Lu S, Shen Q, Zhang L, Zhang J. Song K, et al. Among authors: shen q. J Chem Inf Model. 2017 Sep 25;57(9):2358-2363. doi: 10.1021/acs.jcim.7b00014. Epub 2017 Aug 31. J Chem Inf Model. 2017. PMID: 28825477

8

AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses.

Huang M, Song K, Liu X, Lu S, Shen Q, Wang R, Gao J, Hong Y, Li Q, Ni D, Xu J, Chen G, Zhang J. Huang M, et al. Among authors: shen q. Nucleic Acids Res. 2018 Jul 2;46(W1):W451-W458. doi: 10.1093/nar/gky374. Nucleic Acids Res. 2018. PMID: 29757429 Free PMC article.

9

Unraveling allosteric landscapes of allosterome with ASD.

Liu X, Lu S, Song K, Shen Q, Ni D, Li Q, He X, Zhang H, Wang Q, Chen Y, Li X, Wu J, Sheng C, Chen G, Liu Y, Lu X, Zhang J. Liu X, et al. Among authors: shen q. Nucleic Acids Res. 2020 Jan 8;48(D1):D394-D401. doi: 10.1093/nar/gkz958. Nucleic Acids Res. 2020. PMID: 31665428 Free PMC article.

10

The structural basis of ATP as an allosteric modulator.

Lu S, Huang W, Wang Q, Shen Q, Li S, Nussinov R, Zhang J. Lu S, et al. Among authors: shen q. PLoS Comput Biol. 2014 Sep 11;10(9):e1003831. doi: 10.1371/journal.pcbi.1003831. eCollection 2014 Sep. PLoS Comput Biol. 2014. PMID: 25211773 Free PMC article.

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