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TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy.
Zehender A, Li YN, Lin NY, Stefanica A, Nüchel J, Chen CW, Hsu HH, Zhu H, Ding X, Huang J, Shen L, Györfi AH, Soare A, Rauber S, Bergmann C, Ramming A, Plomann M, Eckes B, Schett G, Distler JHW. Zehender A, et al. Among authors: shen l. Nat Commun. 2021 Jul 20;12(1):4404. doi: 10.1038/s41467-021-24601-y. Nat Commun. 2021. PMID: 34285225 Free PMC article.
PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis.
Zhang Y, Shen L, Zhu H, Dreissigacker K, Distler D, Zhou X, Györfi AH, Bergmann C, Meng X, Dees C, Trinh-Minh T, Ludolph I, Horch R, Ramming A, Schett G, Distler JHW. Zhang Y, et al. Among authors: shen l. Ann Rheum Dis. 2020 Sep;79(9):1227-1233. doi: 10.1136/annrheumdis-2020-216963. Epub 2020 Jun 1. Ann Rheum Dis. 2020. PMID: 32482644
Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease.
Zhang Y, Shen L, Dreißigacker K, Zhu H, Trinh-Minh T, Meng X, Tran-Manh C, Dees C, Matei AE, Chen CW, Ditschkowski M, Krauss S, Winkler J, Wolff D, Ziemer M, Beilhack A, Karrer S, Herr W, Mackensen A, Schett G, Spriewald BM, Distler JHW. Zhang Y, et al. Among authors: shen l. Blood. 2021 Apr 29;137(17):2403-2416. doi: 10.1182/blood.2020008720. Blood. 2021. PMID: 33529322 Free article.
Discovery and engineering of Tsp2Cas9 for genome editing.
Mao H, Tian Y, Wang Z, Liu J, Wei J, Wang Y, Tao C, Li M, Wang S, Shen L, Tang J, Wang R, Gao S, Lan F, Wang Y. Mao H, et al. Among authors: shen l. Cell Discov. 2024 May 21;10(1):55. doi: 10.1038/s41421-024-00685-w. Cell Discov. 2024. PMID: 38769322 No abstract available.
12,661 results
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