Shen J - Search Results

1

Molecular recognition of morphine and fentanyl by the human μ-opioid receptor.

Zhuang Y, Wang Y, He B, He X, Zhou XE, Guo S, Rao Q, Yang J, Liu J, Zhou Q, Wang X, Liu M, Liu W, Jiang X, Yang D, Jiang H, Shen J, Melcher K, Chen H, Jiang Y, Cheng X, Wang MW, Xie X, Xu HE. Zhuang Y, et al. Among authors: shen j. Cell. 2022 Nov 10;185(23):4361-4375.e19. doi: 10.1016/j.cell.2022.09.041. Cell. 2022. PMID: 36368306 Free article.

2

Molecular modeling on kappa opioid receptor and its interaction with nonpeptide kappa opioid agonists.

Liu DX, Jiang HL, Shen JS, Zhu WL, Zhao L, Chen KX, Ji RY. Liu DX, et al. Among authors: shen js. Zhongguo Yao Li Xue Bao. 1999 Feb;20(2):131-6. Zhongguo Yao Li Xue Bao. 1999. PMID: 10437159 Free article.

3

Multiple pharmacophore models combined with molecular docking: a reliable way for efficiently identifying novel PDE4 inhibitors with high structural diversity.

Chen Z, Tian G, Wang Z, Jiang H, Shen J, Zhu W. Chen Z, et al. Among authors: shen j. J Chem Inf Model. 2010 Apr 26;50(4):615-25. doi: 10.1021/ci9004173. J Chem Inf Model. 2010. PMID: 20353193

4

Sildenafil promotes adipogenesis through a PKG pathway.

Zhang X, Ji J, Yan G, Wu J, Sun X, Shen J, Jiang H, Wang H. Zhang X, et al. Among authors: shen j. Biochem Biophys Res Commun. 2010 Jun 11;396(4):1054-9. doi: 10.1016/j.bbrc.2010.05.064. Epub 2010 May 21. Biochem Biophys Res Commun. 2010. PMID: 20471953

5

PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells.

Zhang X, Yan G, Ji J, Wu J, Sun X, Shen J, Jiang H, Wang H. Zhang X, et al. Among authors: shen j. J Cell Biochem. 2012 Aug;113(8):2738-43. doi: 10.1002/jcb.24147. J Cell Biochem. 2012. PMID: 22441938

6

Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5.

Wang G, Liu Z, Chen T, Wang Z, Yang H, Zheng M, Ren J, Tian G, Yang X, Li L, Li J, Suo J, Zhang R, Jiang X, Terrett NK, Shen J, Xu Y, Jiang H. Wang G, et al. Among authors: shen j. J Med Chem. 2012 Dec 13;55(23):10540-50. doi: 10.1021/jm301159y. Epub 2012 Nov 19. J Med Chem. 2012. PMID: 23137303

7

The selectivity and potency of the new PDE5 inhibitor TPN729MA.

Wang Z, Zhu D, Yang X, Li J, Jiang X, Tian G, Terrett NK, Jin J, Wu H, He Q, Yang B, Shen J. Wang Z, et al. Among authors: shen j. J Sex Med. 2013 Nov;10(11):2790-7. doi: 10.1111/jsm.12285. Epub 2013 Aug 12. J Sex Med. 2013. PMID: 23937247

8

Thermodynamic and structural characterization of halogen bonding in protein-ligand interactions: a case study of PDE5 and its inhibitors.

Ren J, He Y, Chen W, Chen T, Wang G, Wang Z, Xu Z, Luo X, Zhu W, Jiang H, Shen J, Xu Y. Ren J, et al. Among authors: shen j. J Med Chem. 2014 Apr 24;57(8):3588-93. doi: 10.1021/jm5002315. Epub 2014 Apr 15. J Med Chem. 2014. PMID: 24702184

9

Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.

Kong X, Chen L, Jiao L, Jiang X, Lian F, Lu J, Zhu K, Du D, Liu J, Ding H, Zhang N, Shen J, Zheng M, Chen K, Liu X, Jiang H, Luo C. Kong X, et al. Among authors: shen j. J Med Chem. 2014 Nov 26;57(22):9512-21. doi: 10.1021/jm501230c. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25369470

10

Design, synthesis, and pharmacological evaluation of highly potent and selective dipeptidyl peptidase-4 inhibitors.

Jiang T, Zhou Y, Zhu J, Chen Z, Sun P, Zhang Q, Wang Z, Shao Q, Jiang X, Li B, Wang H, Zhu W, Shen J. Jiang T, et al. Among authors: shen j. Arch Pharm (Weinheim). 2015 Jun;348(6):399-407. doi: 10.1002/ardp.201500082. Epub 2015 Apr 14. Arch Pharm (Weinheim). 2015. PMID: 25871012

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