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DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse.
Zhou W, Hinoue T, Barnes B, Mitchell O, Iqbal W, Lee SM, Foy KK, Lee KH, Moyer EJ, VanderArk A, Koeman JM, Ding W, Kalkat M, Spix NJ, Eagleson B, Pospisilik JA, Szabó PE, Bartolomei MS, Vander Schaaf NA, Kang L, Wiseman AK, Jones PA, Krawczyk CM, Adams M, Porecha R, Chen BH, Shen H, Laird PW. Zhou W, et al. Among authors: shen h. Cell Genom. 2022 Jul 13;2(7):100144. doi: 10.1016/j.xgen.2022.100144. Cell Genom. 2022. PMID: 35873672 Free PMC article.
Genome-scale analysis of aberrant DNA methylation in colorectal cancer.
Hinoue T, Weisenberger DJ, Lange CP, Shen H, Byun HM, Van Den Berg D, Malik S, Pan F, Noushmehr H, van Dijk CM, Tollenaar RA, Laird PW. Hinoue T, et al. Among authors: shen h. Genome Res. 2012 Feb;22(2):271-82. doi: 10.1101/gr.117523.110. Epub 2011 Jun 9. Genome Res. 2012. PMID: 21659424 Free PMC article.
In epigenetic therapy, less is more.
Shen H, Laird PW. Shen H, et al. Cell Stem Cell. 2012 Apr 6;10(4):353-4. doi: 10.1016/j.stem.2012.03.012. Cell Stem Cell. 2012. PMID: 22482500 Free article.
Inferring tumour purity and stromal and immune cell admixture from expression data.
Yoshihara K, Shahmoradgoli M, Martínez E, Vegesna R, Kim H, Torres-Garcia W, Treviño V, Shen H, Laird PW, Levine DA, Carter SL, Getz G, Stemke-Hale K, Mills GB, Verhaak RG. Yoshihara K, et al. Among authors: shen h. Nat Commun. 2013;4:2612. doi: 10.1038/ncomms3612. Nat Commun. 2013. PMID: 24113773 Free PMC article.
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin.
Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, Leiserson MDM, Niu B, McLellan MD, Uzunangelov V, Zhang J, Kandoth C, Akbani R, Shen H, Omberg L, Chu A, Margolin AA, Van't Veer LJ, Lopez-Bigas N, Laird PW, Raphael BJ, Ding L, Robertson AG, Byers LA, Mills GB, Weinstein JN, Van Waes C, Chen Z, Collisson EA; Cancer Genome Atlas Research Network; Benz CC, Perou CM, Stuart JM. Hoadley KA, et al. Among authors: shen h. Cell. 2014 Aug 14;158(4):929-944. doi: 10.1016/j.cell.2014.06.049. Epub 2014 Aug 7. Cell. 2014. PMID: 25109877 Free PMC article.
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