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Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity.
Bondareva O, Rodríguez-Aguilera JR, Oliveira F, Liao L, Rose A, Gupta A, Singh K, Geier F, Schuster J, Boeckel JN, Buescher JM, Kohli S, Klöting N, Isermann B, Blüher M, Sheikh BN. Bondareva O, et al. Among authors: sheikh bn. Nat Metab. 2022 Nov;4(11):1591-1610. doi: 10.1038/s42255-022-00674-x. Epub 2022 Nov 18. Nat Metab. 2022. PMID: 36400935 Free PMC article.
Career pathways, part 12.
Sheikh BN, Feng YX. Sheikh BN, et al. Nat Metab. 2023 Oct;5(10):1642-1645. doi: 10.1038/s42255-023-00902-y. Nat Metab. 2023. PMID: 37794202 No abstract available.
Leptin treatment has vasculo-protective effects in lipodystrophic mice.
Stürzebecher PE, Kralisch S, Schubert MR, Filipova V, Hoffmann A, Oliveira F, Sheikh BN, Blüher M, Kogel A, Scholz M, Kokot KE, Erbe S, Kneuer JM, Ebert T, Fasshauer M, Miehle K, Laufs U, Tönjes A, Boeckel JN. Stürzebecher PE, et al. Among authors: sheikh bn. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2110374119. doi: 10.1073/pnas.2110374119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161905 Free PMC article.
Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature.
Sheikh BN, Guhathakurta S, Tsang TH, Schwabenland M, Renschler G, Herquel B, Bhardwaj V, Holz H, Stehle T, Bondareva O, Aizarani N, Mossad O, Kretz O, Reichardt W, Chatterjee A, Braun LJ, Thevenon J, Sartelet H, Blank T, Grün D, von Elverfeldt D, Huber TB, Vestweber D, Avilov S, Prinz M, Buescher JM, Akhtar A. Sheikh BN, et al. Nat Cell Biol. 2020 Jul;22(7):828-841. doi: 10.1038/s41556-020-0526-8. Epub 2020 Jun 15. Nat Cell Biol. 2020. PMID: 32541879
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Baell JB, Leaver DJ, Hermans SJ, Kelly GL, Brennan MS, Downer NL, Nguyen N, Wichmann J, McRae HM, Yang Y, Cleary B, Lagiakos HR, Mieruszynski S, Pacini G, Vanyai HK, Bergamasco MI, May RE, Davey BK, Morgan KJ, Sealey AJ, Wang B, Zamudio N, Wilcox S, Garnham AL, Sheikh BN, Aubrey BJ, Doggett K, Chung MC, de Silva M, Bentley J, Pilling P, Hattarki M, Dolezal O, Dennis ML, Falk H, Ren B, Charman SA, White KL, Rautela J, Newbold A, Hawkins ED, Johnstone RW, Huntington ND, Peat TS, Heath JK, Strasser A, Parker MW, Smyth GK, Street IP, Monahan BJ, Voss AK, Thomas T. Baell JB, et al. Among authors: sheikh bn. Nature. 2018 Aug;560(7717):253-257. doi: 10.1038/s41586-018-0387-5. Epub 2018 Aug 1. Nature. 2018. PMID: 30069049
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