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Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness.
Mok S, Yeo T, Hong D, Shears MJ, Ross LS, Ward KE, Dhingra SK, Kanai M, Bridgford JL, Tripathi AK, Mlambo G, Burkhard AY, Ansbro MR, Fairhurst KJ, Gil-Iturbe E, Park H, Rozenberg FD, Kim J, Mancia F, Fairhurst RM, Quick M, Uhlemann AC, Sinnis P, Fidock DA. Mok S, et al. Among authors: shears mj. Sci Adv. 2023 Nov 10;9(45):eadi2364. doi: 10.1126/sciadv.adi2364. Epub 2023 Nov 8. Sci Adv. 2023. PMID: 37939186 Free PMC article.
Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.
McLean KJ, Straimer J, Hopp CS, Vega-Rodriguez J, Small-Saunders JL, Kanatani S, Tripathi A, Mlambo G, Dumoulin PC, Harris CT, Tong X, Shears MJ, Ankarklev J, Kafsack BFC, Fidock DA, Sinnis P. McLean KJ, et al. Among authors: shears mj. Sci Rep. 2019 Sep 11;9(1):13131. doi: 10.1038/s41598-019-49348-x. Sci Rep. 2019. PMID: 31511546 Free PMC article.
Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites.
Lindner SE, Swearingen KE, Shears MJ, Sebastian A, Walker MP, Vrana EN, Hart KJ, Minns AM, Albert I, Sinnis P, Moritz RL, Kappe SHI. Lindner SE, et al. Among authors: shears mj. Nat Commun. 2022 Jan 6;13(1):283. doi: 10.1038/s41467-021-27767-7. Nat Commun. 2022. PMID: 34992211 Free PMC article. No abstract available.
AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes.
Marques-da-Silva C, Poudel B, Baptista RP, Peissig K, Hancox LS, Shiau JC, Pewe LL, Shears MJ, Kanneganti TD, Sinnis P, Kyle DE, Gurung P, Harty JT, Kurup SP. Marques-da-Silva C, et al. Among authors: shears mj. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2210181120. doi: 10.1073/pnas.2210181120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595704 Free PMC article.
Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics.
Swearingen KE, Lindner SE, Shi L, Shears MJ, Harupa A, Hopp CS, Vaughan AM, Springer TA, Moritz RL, Kappe SH, Sinnis P. Swearingen KE, et al. Among authors: shears mj. PLoS Pathog. 2016 Apr 29;12(4):e1005606. doi: 10.1371/journal.ppat.1005606. eCollection 2016 Apr. PLoS Pathog. 2016. PMID: 27128092 Free PMC article.
33 results