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Parkin coregulates glutathione metabolism in adult mammalian brain.
El Kodsi DN, Tokarew JM, Sengupta R, Lengacher NA, Chatterji A, Nguyen AP, Boston H, Jiang Q, Palmberg C, Pileggi C, Holterman CE, Shutinoski B, Li J, Fehr TK, LaVoie MJ, Ratan RR, Shaw GS, Takanashi M, Hattori N, Kennedy CR, Harper ME, Holmgren A, Tomlinson JJ, Schlossmacher MG. El Kodsi DN, et al. Among authors: shaw gs. Acta Neuropathol Commun. 2023 Jan 23;11(1):19. doi: 10.1186/s40478-022-01488-4. Acta Neuropathol Commun. 2023. PMID: 36691076 Free PMC article.
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites.
Tokarew JM, El-Kodsi DN, Lengacher NA, Fehr TK, Nguyen AP, Shutinoski B, O'Nuallain B, Jin M, Khan JM, Ng ACH, Li J, Jiang Q, Zhang M, Wang L, Sengupta R, Barber KR, Tran A, Im DS, Callaghan S, Park DS, Zandee S, Dong X, Scherzer CR, Prat A, Tsai EC, Takanashi M, Hattori N, Chan JA, Zecca L, West AB, Holmgren A, Puente L, Shaw GS, Toth G, Woulfe JM, Taylor P, Tomlinson JJ, Schlossmacher MG. Tokarew JM, et al. Among authors: shaw gs. Acta Neuropathol. 2021 May;141(5):725-754. doi: 10.1007/s00401-021-02285-4. Epub 2021 Mar 10. Acta Neuropathol. 2021. PMID: 33694021 Free PMC article.
A mechanistic review of Parkin activation.
Gundogdu M, Tadayon R, Salzano G, Shaw GS, Walden H. Gundogdu M, et al. Among authors: shaw gs. Biochim Biophys Acta Gen Subj. 2021 Jun;1865(6):129894. doi: 10.1016/j.bbagen.2021.129894. Epub 2021 Mar 20. Biochim Biophys Acta Gen Subj. 2021. PMID: 33753174 Review.
Ataxin-3 is a multivalent ligand for the parkin Ubl domain.
Bai JJ, Safadi SS, Mercier P, Barber KR, Shaw GS. Bai JJ, et al. Among authors: shaw gs. Biochemistry. 2013 Oct 22;52(42):7369-76. doi: 10.1021/bi400780v. Epub 2013 Oct 9. Biochemistry. 2013. PMID: 24063750 Free PMC article.
131 results