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Viral defense: it takes two MAVS to Tango.
Sharma S, Fitzgerald KA. Sharma S, et al. Cell. 2010 May 14;141(4):570-2. doi: 10.1016/j.cell.2010.04.043. Cell. 2010. PMID: 20478250 Free article.
Catenin' on to nucleic acid sensing.
Rathinam VA, Sharma S, Fitzgerald KA. Rathinam VA, et al. Among authors: sharma s. Nat Immunol. 2010 Jun;11(6):466-8. doi: 10.1038/ni0610-466. Nat Immunol. 2010. PMID: 20485273 No abstract available.
IFI16 is an innate immune sensor for intracellular DNA.
Unterholzner L, Keating SE, Baran M, Horan KA, Jensen SB, Sharma S, Sirois CM, Jin T, Latz E, Xiao TS, Fitzgerald KA, Paludan SR, Bowie AG. Unterholzner L, et al. Among authors: sharma s. Nat Immunol. 2010 Nov;11(11):997-1004. doi: 10.1038/ni.1932. Epub 2010 Oct 3. Nat Immunol. 2010. PMID: 20890285 Free PMC article.
Innate immune sensing of DNA.
Sharma S, Fitzgerald KA. Sharma S, et al. PLoS Pathog. 2011 Apr;7(4):e1001310. doi: 10.1371/journal.ppat.1001310. Epub 2011 Apr 21. PLoS Pathog. 2011. PMID: 21533068 Free PMC article. Review. No abstract available.
Interferon γ-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA viruses.
Thompson MR, Sharma S, Atianand M, Jensen SB, Carpenter S, Knipe DM, Fitzgerald KA, Kurt-Jones EA. Thompson MR, et al. Among authors: sharma s. J Biol Chem. 2014 Aug 22;289(34):23568-81. doi: 10.1074/jbc.M114.554147. Epub 2014 Jul 7. J Biol Chem. 2014. PMID: 25002588 Free PMC article.
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