Shao Z - Search Results

1

Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.

Xiao P, Yan W, Gou L, Zhong YN, Kong L, Wu C, Wen X, Yuan Y, Cao S, Qu C, Yang X, Yang CC, Xia A, Hu Z, Zhang Q, He YH, Zhang DL, Zhang C, Hou GH, Liu H, Zhu L, Fu P, Yang S, Rosenbaum DM, Sun JP, Du Y, Zhang L, Yu X, Shao Z. Xiao P, et al. Among authors: shao z. Cell. 2021 Feb 18;184(4):943-956.e18. doi: 10.1016/j.cell.2021.01.028. Epub 2021 Feb 10. Cell. 2021. PMID: 33571432 Free PMC article.

2

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.

Yin J, Babaoglu K, Brautigam CA, Clark L, Shao Z, Scheuermann TH, Harrell CM, Gotter AL, Roecker AJ, Winrow CJ, Renger JJ, Coleman PJ, Rosenbaum DM. Yin J, et al. Among authors: shao z. Nat Struct Mol Biol. 2016 Apr;23(4):293-9. doi: 10.1038/nsmb.3183. Epub 2016 Mar 7. Nat Struct Mol Biol. 2016. PMID: 26950369

3

High-resolution crystal structure of the human CB1 cannabinoid receptor.

Shao Z, Yin J, Chapman K, Grzemska M, Clark L, Wang J, Rosenbaum DM. Shao Z, et al. Nature. 2016 Dec 22;540(7634):602-606. doi: 10.1038/nature20613. Epub 2016 Nov 16. Nature. 2016. PMID: 27851727 Free PMC article.

4

Crystal structure of the human NK₁ tachykinin receptor.

Yin J, Chapman K, Clark LD, Shao Z, Borek D, Xu Q, Wang J, Rosenbaum DM. Yin J, et al. Among authors: shao z. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13264-13269. doi: 10.1073/pnas.1812717115. Epub 2018 Dec 11. Proc Natl Acad Sci U S A. 2018. PMID: 30538204 Free PMC article.

5

Structure of an allosteric modulator bound to the CB1 cannabinoid receptor.

Shao Z, Yan W, Chapman K, Ramesh K, Ferrell AJ, Yin J, Wang X, Xu Q, Rosenbaum DM. Shao Z, et al. Nat Chem Biol. 2019 Dec;15(12):1199-1205. doi: 10.1038/s41589-019-0387-2. Epub 2019 Oct 28. Nat Chem Biol. 2019. PMID: 31659318

6

Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode.

Yan W, Cheng L, Wang W, Wu C, Yang X, Du X, Ma L, Qi S, Wei Y, Lu Z, Yang S, Shao Z. Yan W, et al. Among authors: shao z. Nat Commun. 2020 Oct 20;11(1):5287. doi: 10.1038/s41467-020-19109-w. Nat Commun. 2020. PMID: 33082324 Free PMC article.

7

Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition.

Yuan Y, Jia G, Wu C, Wang W, Cheng L, Li Q, Li Z, Luo K, Yang S, Yan W, Su Z, Shao Z. Yuan Y, et al. Among authors: shao z. Cell Res. 2021 Dec;31(12):1263-1274. doi: 10.1038/s41422-021-00566-x. Epub 2021 Sep 15. Cell Res. 2021. PMID: 34526663 Free PMC article.

8

Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3-Gi signaling complexes.

Zhao C, Cheng L, Wang W, Wang H, Luo Y, Feng Y, Wang X, Fu H, Cai Y, Yang S, Fu P, Yan W, Shao Z. Zhao C, et al. Among authors: shao z. Cell Res. 2022 Feb;32(2):218-221. doi: 10.1038/s41422-021-00567-w. Epub 2021 Sep 20. Cell Res. 2022. PMID: 34545189 Free PMC article. No abstract available.

9

Molecular mechanism of agonism and inverse agonism in ghrelin receptor.

Qin J, Cai Y, Xu Z, Ming Q, Ji SY, Wu C, Zhang H, Mao C, Shen DD, Hirata K, Ma Y, Yan W, Zhang Y, Shao Z. Qin J, et al. Among authors: shao z. Nat Commun. 2022 Jan 13;13(1):300. doi: 10.1038/s41467-022-27975-9. Nat Commun. 2022. PMID: 35027551 Free PMC article.

10

Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1.

Yang X, Wang X, Xu Z, Wu C, Zhou Y, Wang Y, Lin G, Li K, Wu M, Xia A, Liu J, Cheng L, Zou J, Yan W, Shao Z, Yang S. Yang X, et al. Among authors: shao z. Nat Chem Biol. 2022 Aug;18(8):831-840. doi: 10.1038/s41589-022-01038-y. Epub 2022 May 30. Nat Chem Biol. 2022. PMID: 35637350

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