Shang R - Search Results

1

Differential requirement of Hippo cascade during CTNNB1 or AXIN1 mutation-driven hepatocarcinogenesis.

Liang B, Wang H, Qiao Y, Wang X, Qian M, Song X, Zhou Y, Zhang Y, Shang R, Che L, Chen Y, Huang Z, Wu H, Monga SP, Zeng Y, Calvisi DF, Chen X, Chen X. Liang B, et al. Among authors: shang r. Hepatology. 2023 Jun 1;77(6):1929-1942. doi: 10.1002/hep.32693. Epub 2022 Oct 18. Hepatology. 2023. PMID: 35921500

2

Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice.

Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang B, Monga SP, Chen X. Qiao Y, et al. Among authors: shang r. Hepatology. 2019 Dec;70(6):2003-2017. doi: 10.1002/hep.30556. Epub 2019 Apr 11. Hepatology. 2019. PMID: 30737831 Free PMC article.

3

The mTORC2-Akt1 Cascade Is Crucial for c-Myc to Promote Hepatocarcinogenesis in Mice and Humans.

Xu Z, Xu M, Liu P, Zhang S, Shang R, Qiao Y, Che L, Ribback S, Cigliano A, Evert K, Pascale RM, Dombrowski F, Evert M, Chen X, Calvisi DF, Chen X. Xu Z, et al. Among authors: shang r. Hepatology. 2019 Nov;70(5):1600-1613. doi: 10.1002/hep.30697. Epub 2019 Jun 21. Hepatology. 2019. PMID: 31062368 Free PMC article.

4

Therapeutic efficacy of FASN inhibition in preclinical models of HCC.

Wang H, Zhou Y, Xu H, Wang X, Zhang Y, Shang R, O'Farrell M, Roessler S, Sticht C, Stahl A, Evert M, Calvisi DF, Zeng Y, Chen X. Wang H, et al. Among authors: shang r. Hepatology. 2022 Oct;76(4):951-966. doi: 10.1002/hep.32359. Epub 2022 Feb 16. Hepatology. 2022. PMID: 35076948 Free PMC article.

5

Oncogene-dependent function of BRG1 in hepatocarcinogenesis.

Wang P, Song X, Cao D, Cui K, Wang J, Utpatel K, Shang R, Wang H, Che L, Evert M, Zhao K, Calvisi DF, Chen X. Wang P, et al. Among authors: shang r. Cell Death Dis. 2020 Feb 4;11(2):91. doi: 10.1038/s41419-020-2289-3. Cell Death Dis. 2020. PMID: 32019910 Free PMC article.

6

mTORC2 Signaling Is Necessary for Timely Liver Regeneration after Partial Hepatectomy.

Xu M, Wang H, Wang J, Burhan D, Shang R, Wang P, Zhou Y, Li R, Liang B, Evert K, Utpatel K, Xu Z, Song X, Che L, Calvisi DF, Wang B, Chen X, Zeng Y, Chen X. Xu M, et al. Among authors: shang r. Am J Pathol. 2020 Apr;190(4):817-829. doi: 10.1016/j.ajpath.2019.12.010. Epub 2020 Feb 5. Am J Pathol. 2020. PMID: 32035060 Free PMC article.

7

Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma.

Shang R, Song X, Wang P, Zhou Y, Lu X, Wang J, Xu M, Chen X, Utpatel K, Che L, Liang B, Cigliano A, Evert M, Calvisi DF, Chen X. Shang R, et al. Gut. 2021 Sep;70(9):1746-1757. doi: 10.1136/gutjnl-2020-320716. Epub 2020 Nov 3. Gut. 2021. PMID: 33144318 Free PMC article.

8

MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment.

Wang P, Song X, Utpatel K, Shang R, Yang YM, Xu M, Zhang J, Che L, Gordan J, Cigliano A, Seki E, Evert M, Calvisi DF, Hu X, Chen X. Wang P, et al. Among authors: shang r. Cell Death Dis. 2019 Feb 11;10(2):120. doi: 10.1038/s41419-019-1389-4. Cell Death Dis. 2019. PMID: 30741922 Free PMC article.

9

SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial-Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model.

Xu M, Wang J, Xu Z, Li R, Wang P, Shang R, Cigliano A, Ribback S, Solinas A, Pes GM, Evert K, Wang H, Song X, Zhang S, Che L, Pascale RM, Calvisi DF, Liu Q, Chen X. Xu M, et al. Among authors: shang r. Cancer Res. 2019 Nov 1;79(21):5563-5574. doi: 10.1158/0008-5472.CAN-18-3750. Epub 2019 Aug 5. Cancer Res. 2019. PMID: 31383647 Free PMC article.

10

Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma.

Xu H, Chen K, Shang R, Chen X, Zhang Y, Song X, Evert M, Zhong S, Li B, Calvisi DF, Chen X. Xu H, et al. Among authors: shang r. Cell Death Dis. 2021 Oct 8;12(10):920. doi: 10.1038/s41419-021-04206-5. Cell Death Dis. 2021. PMID: 34625531 Free PMC article.

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