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CARD8 is an inflammasome sensor for HIV-1 protease activity.
Wang Q, Gao H, Clark KM, Mugisha CS, Davis K, Tang JP, Harlan GH, DeSelm CJ, Presti RM, Kutluay SB, Shan L. Wang Q, et al. Among authors: shan l. Science. 2021 Mar 19;371(6535):eabe1707. doi: 10.1126/science.abe1707. Epub 2021 Feb 4. Science. 2021. PMID: 33542150 Free PMC article.
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells.
Song Y, Shan L, Gbyli R, Liu W, Strowig T, Patel A, Fu X, Wang X, Xu ML, Gao Y, Qin A, Bruscia EM, Tebaldi T, Biancon G, Mamillapalli P, Urbonas D, Eynon E, Gonzalez DG, Chen J, Krause DS, Alderman J, Halene S, Flavell RA. Song Y, et al. Among authors: shan l. Science. 2021 Mar 5;371(6533):1019-1025. doi: 10.1126/science.abe2485. Science. 2021. PMID: 33674488 Free PMC article.
CARD8 makes coxsackievirus more "heartbreaking".
Wang Q, Shan L. Wang Q, et al. Among authors: shan l. J Exp Med. 2022 Oct 3;219(10):e20221240. doi: 10.1084/jem.20221240. Epub 2022 Sep 21. J Exp Med. 2022. PMID: 36129454 Free PMC article.
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF. Deng K, et al. Among authors: shan l. Nature. 2015 Jan 15;517(7534):381-5. doi: 10.1038/nature14053. Epub 2015 Jan 7. Nature. 2015. PMID: 25561180 Free PMC article.
Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.
Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, Zhao Y, Jurado KA, Feng N, Shan L, Kluger Y, Lu J, Abraham C, Fikrig E, Greenberg HB, Flavell RA. Zhu S, et al. Among authors: shan l. Nature. 2017 Jun 29;546(7660):667-670. doi: 10.1038/nature22967. Epub 2017 Jun 21. Nature. 2017. PMID: 28636595 Free PMC article.
2,527 results