Sham YY - Search Results

1

Kinetic Characterization and Computational Modeling of Escherichia coli Heptosyltransferase II: Exploring the Role of Protein Dynamics in Catalysis for GT-B Glycosyltransferase.

Hassan BA, Liu ZA, Milicaj J, Kim MS, Tyson M, Sham YY, Taylor EA. Hassan BA, et al. Among authors: sham yy. Biochemistry. 2022 Aug 2;61(15):1572-1584. doi: 10.1021/acs.biochem.2c00329. Epub 2022 Jul 21. Biochemistry. 2022. PMID: 35861590

2

Impact of the C-terminal loop of histidine triad nucleotide binding protein1 (Hint1) on substrate specificity.

Chou TF, Sham YY, Wagner CR. Chou TF, et al. Among authors: sham yy. Biochemistry. 2007 Nov 13;46(45):13074-9. doi: 10.1021/bi701244h. Epub 2007 Oct 16. Biochemistry. 2007. PMID: 17939685

3

The Stories Tryptophans Tell: Exploring Protein Dynamics of Heptosyltransferase I from Escherichia coli.

Cote JM, Ramirez-Mondragon CA, Siegel ZS, Czyzyk DJ, Gao J, Sham YY, Mukerji I, Taylor EA. Cote JM, et al. Among authors: sham yy. Biochemistry. 2017 Feb 14;56(6):886-895. doi: 10.1021/acs.biochem.6b00850. Epub 2017 Jan 30. Biochemistry. 2017. PMID: 28098447 Free PMC article.

4

Maintenance DNA Methyltransferase Activity in the Presence of Oxidized Forms of 5-Methylcytosine: Structural Basis for Ten Eleven Translocation-Mediated DNA Demethylation.

Seiler CL, Fernandez J, Koerperich Z, Andersen MP, Kotandeniya D, Nguyen ME, Sham YY, Tretyakova NY. Seiler CL, et al. Among authors: sham yy. Biochemistry. 2018 Oct 23;57(42):6061-6069. doi: 10.1021/acs.biochem.8b00683. Epub 2018 Oct 8. Biochemistry. 2018. PMID: 30230311 Free PMC article.

5

Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between the Substrate and Positively Charged Residues.

Cote JM, Hecht CJS, Patel KR, Ramirez-Mondragon CA, Sham YY, Taylor EA. Cote JM, et al. Among authors: sham yy. Biochemistry. 2020 Sep 1;59(34):3135-3147. doi: 10.1021/acs.biochem.9b01005. Epub 2020 Feb 10. Biochemistry. 2020. PMID: 32011131 Free PMC article.

6

Conserved Conformational Hierarchy across Functionally Divergent Glycosyltransferases of the GT-B Structural Superfamily as Determined from Microsecond Molecular Dynamics.

Ramirez-Mondragon CA, Nguyen ME, Milicaj J, Hassan BA, Tucci FJ, Muthyala R, Gao J, Taylor EA, Sham YY. Ramirez-Mondragon CA, et al. Among authors: sham yy. Int J Mol Sci. 2021 Apr 28;22(9):4619. doi: 10.3390/ijms22094619. Int J Mol Sci. 2021. PMID: 33924837 Free PMC article.

7

Ligand-Induced Conformational and Dynamical Changes in a GT-B Glycosyltransferase: Molecular Dynamics Simulations of Heptosyltransferase I Complexes.

Hassan BA, Milicaj J, Ramirez-Mondragon CA, Sham YY, Taylor EA. Hassan BA, et al. Among authors: sham yy. J Chem Inf Model. 2022 Jan 24;62(2):324-339. doi: 10.1021/acs.jcim.1c00868. Epub 2021 Dec 30. J Chem Inf Model. 2022. PMID: 34967618 Free PMC article.

8

Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action.

Milicaj J, Hassan BA, Cote JM, Ramirez-Mondragon CA, Jaunbocus N, Rafalowski A, Patel KR, Castro CD, Muthyala R, Sham YY, Taylor EA. Milicaj J, et al. Among authors: sham yy. Sci Rep. 2022 May 4;12(1):7302. doi: 10.1038/s41598-022-10776-x. Sci Rep. 2022. PMID: 35508636 Free PMC article.

9

Molecular dynamics simulation of Escherichia coli dihydrofolate reductase and its protein fragments: relative stabilities in experiment and simulations.

Sham YY, Ma B, Tsai CJ, Nussinov R. Sham YY, et al. Protein Sci. 2001 Jan;10(1):135-48. doi: 10.1110/ps.33301. Protein Sci. 2001. PMID: 11266602 Free PMC article.

10

Thermal unfolding molecular dynamics simulation of Escherichia coli dihydrofolate reductase: thermal stability of protein domains and unfolding pathway.

Sham YY, Ma B, Tsai CJ, Nussinov R. Sham YY, et al. Proteins. 2002 Feb 15;46(3):308-20. doi: 10.1002/prot.10040. Proteins. 2002. PMID: 11835506

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