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Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.
Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakhshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S. Martins MM, et al. Among authors: shales m. Cancer Discov. 2015 Feb;5(2):154-67. doi: 10.1158/2159-8290.CD-14-0552. Epub 2014 Dec 12. Cancer Discov. 2015. PMID: 25501949 Free PMC article.
Quantitative genetic-interaction mapping in mammalian cells.
Roguev A, Talbot D, Negri GL, Shales M, Cagney G, Bandyopadhyay S, Panning B, Krogan NJ. Roguev A, et al. Among authors: shales m. Nat Methods. 2013 May;10(5):432-7. doi: 10.1038/nmeth.2398. Epub 2013 Feb 13. Nat Methods. 2013. PMID: 23407553 Free PMC article.
Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.
Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM. Kliegman JI, et al. Among authors: shales m. Cell Rep. 2013 Dec 26;5(6):1725-36. doi: 10.1016/j.celrep.2013.11.040. Epub 2013 Dec 19. Cell Rep. 2013. PMID: 24360963 Free PMC article.
Differential genetic interactions of yeast stress response MAPK pathways.
Martin H, Shales M, Fernandez-Piñar P, Wei P, Molina M, Fiedler D, Shokat KM, Beltrao P, Lim W, Krogan NJ. Martin H, et al. Among authors: shales m. Mol Syst Biol. 2015 Apr 17;11(4):800. doi: 10.15252/msb.20145606. Mol Syst Biol. 2015. PMID: 25888283 Free PMC article.
Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.
Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, Krogan NJ. Roguev A, et al. Among authors: shales m. Science. 2008 Oct 17;322(5900):405-10. doi: 10.1126/science.1162609. Epub 2008 Sep 25. Science. 2008. PMID: 18818364 Free PMC article.
Functional organization of the S. cerevisiae phosphorylation network.
Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ. Fiedler D, et al. Among authors: shales m. Cell. 2009 Mar 6;136(5):952-63. doi: 10.1016/j.cell.2008.12.039. Cell. 2009. PMID: 19269370 Free PMC article.
Quantitative analysis of triple-mutant genetic interactions.
Braberg H, Alexander R, Shales M, Xu J, Franks-Skiba KE, Wu Q, Haber JE, Krogan NJ. Braberg H, et al. Among authors: shales m. Nat Protoc. 2014 Aug;9(8):1867-81. doi: 10.1038/nprot.2014.127. Epub 2014 Jul 10. Nat Protoc. 2014. PMID: 25010907 Free PMC article.
Genetic interaction mapping in mammalian cells using CRISPR interference.
Du D, Roguev A, Gordon DE, Chen M, Chen SH, Shales M, Shen JP, Ideker T, Mali P, Qi LS, Krogan NJ. Du D, et al. Among authors: shales m. Nat Methods. 2017 Jun;14(6):577-580. doi: 10.1038/nmeth.4286. Epub 2017 May 8. Nat Methods. 2017. PMID: 28481362 Free PMC article.
48 results