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PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.
Berger A, Hoelbl-Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, Uras IZ, Menzl I, Putz EM, Hoermann G, Schuster C, Fajmann S, Leitner E, Kubicek S, Moriggl R, Gouilleux F, Sexl V. Berger A, et al. Among authors: sexl v. Leukemia. 2014 Mar;28(3):629-41. doi: 10.1038/leu.2013.351. Epub 2013 Nov 22. Leukemia. 2014. PMID: 24263804 Free PMC article.
Loss of STAT3 in Lymphoma Relaxes NK Cell-Mediated Tumor Surveillance.
Putz EM, Hoelzl MA, Baeck J, Bago-Horvath Z, Schuster C, Reichholf B, Kern D, Aberger F, Sexl V, Hoelbl-Kovacic A. Putz EM, et al. Among authors: sexl v. Cancers (Basel). 2014 Jan 27;6(1):193-210. doi: 10.3390/cancers6010193. Cancers (Basel). 2014. PMID: 24473086 Free PMC article.
Acceleration of Bcr-Abl+ leukemia induced by deletion of JAK2.
Grundschober E, Hoelbl-Kovacic A, Bhagwat N, Kovacic B, Scheicher R, Eckelhart E, Kollmann K, Keller M, Grebien F, Wagner KU, Levine RL, Sexl V. Grundschober E, et al. Among authors: sexl v. Leukemia. 2014 Sep;28(9):1918-22. doi: 10.1038/leu.2014.152. Epub 2014 May 5. Leukemia. 2014. PMID: 24791858 Free PMC article. No abstract available.
CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.
Scheicher R, Hoelbl-Kovacic A, Bellutti F, Tigan AS, Prchal-Murphy M, Heller G, Schneckenleithner C, Salazar-Roa M, Zöchbauer-Müller S, Zuber J, Malumbres M, Kollmann K, Sexl V. Scheicher R, et al. Among authors: sexl v. Blood. 2015 Jan 1;125(1):90-101. doi: 10.1182/blood-2014-06-584417. Epub 2014 Oct 23. Blood. 2015. PMID: 25342715 Free PMC article.
Modeling BCR/ABL-driven malignancies in the mouse.
Schneckenleithner C, Hoelbl-Kovacic A, Sexl V. Schneckenleithner C, et al. Among authors: sexl v. Methods Mol Biol. 2015;1267:263-82. doi: 10.1007/978-1-4939-2297-0_12. Methods Mol Biol. 2015. PMID: 25636473
Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.
Sadovnik I, Hoelbl-Kovacic A, Herrmann H, Eisenwort G, Cerny-Reiterer S, Warsch W, Hoermann G, Greiner G, Blatt K, Peter B, Stefanzl G, Berger D, Bilban M, Herndlhofer S, Sill H, Sperr WR, Streubel B, Mannhalter C, Holyoake TL, Sexl V, Valent P. Sadovnik I, et al. Among authors: sexl v. Clin Cancer Res. 2016 Apr 15;22(8):2051-61. doi: 10.1158/1078-0432.CCR-15-0767. Epub 2015 Nov 25. Clin Cancer Res. 2016. PMID: 26607600 Free PMC article.
It is a differentiation game: STAT5 in a new role.
Maurer B, Farlik M, Sexl V. Maurer B, et al. Among authors: sexl v. Cell Death Differ. 2017 Jun;24(6):953-954. doi: 10.1038/cdd.2017.71. Epub 2017 May 12. Cell Death Differ. 2017. PMID: 28498368 Free PMC article. No abstract available.
205 results