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Amyloid-induced β-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment.
Montane J, de Pablo S, Castaño C, Rodríguez-Comas J, Cadavez L, Obach M, Visa M, Alcarraz-Vizán G, Sanchez-Martinez M, Nonell-Canals A, Parrizas M, Servitja JM, Novials A. Montane J, et al. Among authors: servitja jm. FASEB J. 2017 Dec;31(12):5296-5306. doi: 10.1096/fj.201700236R. Epub 2017 Aug 15. FASEB J. 2017. PMID: 28821639 Free PMC article.
Circulating miR-192 and miR-193b are markers of prediabetes and are modulated by an exercise intervention.
Párrizas M, Brugnara L, Esteban Y, González-Franquesa A, Canivell S, Murillo S, Gordillo-Bastidas E, Cussó R, Cadefau JA, García-Roves PM, Servitja JM, Novials A. Párrizas M, et al. Among authors: servitja jm. J Clin Endocrinol Metab. 2015 Mar;100(3):E407-15. doi: 10.1210/jc.2014-2574. Epub 2014 Dec 22. J Clin Endocrinol Metab. 2015. PMID: 25532038 Clinical Trial.
Stress-Induced MicroRNA-708 Impairs β-Cell Function and Growth.
Rodríguez-Comas J, Moreno-Asso A, Moreno-Vedia J, Martín M, Castaño C, Marzà-Florensa A, Bofill-De Ros X, Mir-Coll J, Montané J, Fillat C, Gasa R, Novials A, Servitja JM. Rodríguez-Comas J, et al. Among authors: servitja jm. Diabetes. 2017 Dec;66(12):3029-3040. doi: 10.2337/db16-1569. Epub 2017 Oct 2. Diabetes. 2017. PMID: 28970284
The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.
Mellado-Gil JM, Fuente-Martín E, Lorenzo PI, Cobo-Vuilleumier N, López-Noriega L, Martín-Montalvo A, Gómez IGH, Ceballos-Chávez M, Gómez-Jaramillo L, Campos-Caro A, Romero-Zerbo SY, Rodríguez-Comas J, Servitja JM, Rojo-Martinez G, Hmadcha A, Soria B, Bugliani M, Marchetti P, Bérmudez-Silva FJ, Reyes JC, Aguilar-Diosdado M, Gauthier BR. Mellado-Gil JM, et al. Among authors: servitja jm. Cell Death Dis. 2018 Feb 15;9(3):279. doi: 10.1038/s41419-018-0272-z. Cell Death Dis. 2018. PMID: 29449530 Free PMC article.
45 results