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PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.
Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA. Knafo S, et al. Among authors: serrano m. Nat Neurosci. 2016 Mar;19(3):443-53. doi: 10.1038/nn.4225. Epub 2016 Jan 18. Nat Neurosci. 2016. PMID: 26780512
PTEN in cancer, metabolism, and aging.
Ortega-Molina A, Serrano M. Ortega-Molina A, et al. Among authors: serrano m. Trends Endocrinol Metab. 2013 Apr;24(4):184-9. doi: 10.1016/j.tem.2012.11.002. Epub 2012 Dec 12. Trends Endocrinol Metab. 2013. PMID: 23245767 Free PMC article. Review.
Delayed ageing through damage protection by the Arf/p53 pathway.
Matheu A, Maraver A, Klatt P, Flores I, Garcia-Cao I, Borras C, Flores JM, Viña J, Blasco MA, Serrano M. Matheu A, et al. Among authors: serrano m. Nature. 2007 Jul 19;448(7151):375-9. doi: 10.1038/nature05949. Nature. 2007. PMID: 17637672
Pten positively regulates brown adipose function, energy expenditure, and longevity.
Ortega-Molina A, Efeyan A, Lopez-Guadamillas E, Muñoz-Martin M, Gómez-López G, Cañamero M, Mulero F, Pastor J, Martinez S, Romanos E, Mar Gonzalez-Barroso M, Rial E, Valverde AM, Bischoff JR, Serrano M. Ortega-Molina A, et al. Among authors: serrano m. Cell Metab. 2012 Mar 7;15(3):382-94. doi: 10.1016/j.cmet.2012.02.001. Cell Metab. 2012. PMID: 22405073 Free article.
G6PD protects from oxidative damage and improves healthspan in mice.
Nóbrega-Pereira S, Fernandez-Marcos PJ, Brioche T, Gomez-Cabrera MC, Salvador-Pascual A, Flores JM, Viña J, Serrano M. Nóbrega-Pereira S, et al. Among authors: serrano m. Nat Commun. 2016 Mar 15;7:10894. doi: 10.1038/ncomms10894. Nat Commun. 2016. PMID: 26976705 Free PMC article.
The PTEN/NRF2 axis promotes human carcinogenesis.
Rojo AI, Rada P, Mendiola M, Ortega-Molina A, Wojdyla K, Rogowska-Wrzesinska A, Hardisson D, Serrano M, Cuadrado A. Rojo AI, et al. Among authors: serrano m. Antioxid Redox Signal. 2014 Dec 20;21(18):2498-514. doi: 10.1089/ars.2014.5843. Epub 2014 Jul 31. Antioxid Redox Signal. 2014. PMID: 24892215 Free PMC article.
Regulation of the tumor suppressor PTEN by SUMO.
González-Santamaría J, Campagna M, Ortega-Molina A, Marcos-Villar L, de la Cruz-Herrera CF, González D, Gallego P, Lopitz-Otsoa F, Esteban M, Rodríguez MS, Serrano M, Rivas C. González-Santamaría J, et al. Among authors: serrano m. Cell Death Dis. 2012 Sep 27;3(9):e393. doi: 10.1038/cddis.2012.135. Cell Death Dis. 2012. PMID: 23013792 Free PMC article.
Anti-aging activity of the Ink4/Arf locus.
Matheu A, Maraver A, Collado M, Garcia-Cao I, Cañamero M, Borras C, Flores JM, Klatt P, Viña J, Serrano M. Matheu A, et al. Among authors: serrano m. Aging Cell. 2009 Apr;8(2):152-61. doi: 10.1111/j.1474-9726.2009.00458.x. Aging Cell. 2009. PMID: 19239418 Free article.
1,949 results