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High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice.
Serrano J, Smith KR, Crouch AL, Sharma V, Yi F, Vargova V, LaMoia TE, Dupont LM, Serna V, Tang F, Gomes-Dias L, Blakeslee JJ, Hatzakis E, Peterson SN, Anderson M, Pratley RE, Kyriazis GA. Serrano J, et al. Among authors: serna v. Microbiome. 2021 Jan 12;9(1):11. doi: 10.1186/s40168-020-00976-w. Microbiome. 2021. PMID: 33431052 Free PMC article. Clinical Trial.
The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans.
Serrano J, Seflova J, Park J, Pribadi M, Sanematsu K, Shigemura N, Serna V, Yi F, Mari A, Procko E, Pratley RE, Robia SL, Kyriazis GA. Serrano J, et al. Among authors: serna v. Mol Metab. 2021 Dec;54:101339. doi: 10.1016/j.molmet.2021.101339. Epub 2021 Sep 9. Mol Metab. 2021. PMID: 34509698 Free PMC article.
Role of stem cells in human uterine leiomyoma growth.
Ono M, Qiang W, Serna VA, Yin P, Coon JS 5th, Navarro A, Monsivais D, Kakinuma T, Dyson M, Druschitz S, Unno K, Kurita T, Bulun SE. Ono M, et al. PLoS One. 2012;7(5):e36935. doi: 10.1371/journal.pone.0036935. Epub 2012 May 3. PLoS One. 2012. PMID: 22570742 Free PMC article.
Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth.
Ono M, Yin P, Navarro A, Moravek MB, Coon JS 5th, Druschitz SA, Serna VA, Qiang W, Brooks DC, Malpani SS, Ma J, Ercan CM, Mittal N, Monsivais D, Dyson MT, Yemelyanov A, Maruyama T, Chakravarti D, Kim JJ, Kurita T, Gottardi CJ, Bulun SE. Ono M, et al. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17053-8. doi: 10.1073/pnas.1313650110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082114 Free PMC article. Clinical Trial.
30 results