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Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease.
Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Astakhova TY, Timokhina EN, Serebryakova OG, Shchepochkin AV, Averkov MA, Utepova IA, Demina NS, Radchenko EV, Palyulin VA, Fisenko VP, Bachurin SO, Chupakhin ON, Charushin VN, Richardson RJ. Makhaeva GF, et al. Among authors: serebryakova og. Front Pharmacol. 2023 Aug 9;14:1219980. doi: 10.3389/fphar.2023.1219980. eCollection 2023. Front Pharmacol. 2023. PMID: 37654616 Free PMC article.
9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment.
Makhaeva GF, Lushchekina SV, Boltneva NP, Serebryakova OG, Rudakova EV, Ustyugov AA, Bachurin SO, Shchepochkin AV, Chupakhin ON, Charushin VN, Richardson RJ. Makhaeva GF, et al. Among authors: serebryakova og. Bioorg Med Chem. 2017 Nov 1;25(21):5981-5994. doi: 10.1016/j.bmc.2017.09.028. Epub 2017 Sep 20. Bioorg Med Chem. 2017. PMID: 28986116
Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics.
Makhaeva GF, Boltneva NP, Lushchekina SV, Rudakova EV, Serebryakova OG, Kulikova LN, Beloglazkin AA, Borisov RS, Richardson RJ. Makhaeva GF, et al. Among authors: serebryakova og. Bioorg Med Chem. 2018 Sep 1;26(16):4716-4725. doi: 10.1016/j.bmc.2018.08.010. Epub 2018 Aug 6. Bioorg Med Chem. 2018. PMID: 30104121
Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
Makhaeva GF, Lushchekina SV, Kovaleva NV, Yu Astakhova T, Boltneva NP, Rudakova EV, Serebryakova OG, Proshin AN, Serkov IV, Trofimova TP, Tafeenko VA, Radchenko EV, Palyulin VA, Fisenko VP, Korábečný J, Soukup O, Richardson RJ. Makhaeva GF, et al. Among authors: serebryakova og. Bioorg Chem. 2021 Jul;112:104974. doi: 10.1016/j.bioorg.2021.104974. Epub 2021 May 21. Bioorg Chem. 2021. PMID: 34029971
Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Grishchenko MV, Lushchekina SV, Astakhova TY, Serebryakova OG, Timokhina EN, Zhilina EF, Shchegolkov EV, Ulitko MV, Radchenko EV, Palyulin VA, Burgart YV, Saloutin VI, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: serebryakova og. Int J Mol Sci. 2023 Jan 24;24(3):2285. doi: 10.3390/ijms24032285. Int J Mol Sci. 2023. PMID: 36768608 Free PMC article.
Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors.
Makhaeva GF, Boltneva NP, Lushchekina SV, Serebryakova OG, Stupina TS, Terentiev AA, Serkov IV, Proshin AN, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: serebryakova og. Bioorg Med Chem. 2016 Mar 1;24(5):1050-62. doi: 10.1016/j.bmc.2016.01.031. Epub 2016 Jan 18. Bioorg Med Chem. 2016. PMID: 26827140
22 results