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Plant cells as pharmaceutical factories.
Rischer H, Häkkinen ST, Ritala A, Seppänen-Laakso T, Miralpeix B, Capell T, Christou P, Oksman-Caldentey KM. Rischer H, et al. Curr Pharm Des. 2013;19(31):5640-60. doi: 10.2174/1381612811319310017. Curr Pharm Des. 2013. PMID: 23394561 Review.
Metabolic engineering of plant secondary products: which way forward?
Miralpeix B, Rischer H, Häkkinen ST, Ritala A, Seppänen-Laakso T, Oksman-Caldentey KM, Capell T, Christou P. Miralpeix B, et al. Curr Pharm Des. 2013;19(31):5622-39. doi: 10.2174/1381612811319310016. Curr Pharm Des. 2013. PMID: 23394556 Review.
Effects of ellagitannin-rich berries on blood lipids, gut microbiota, and urolithin production in human subjects with symptoms of metabolic syndrome.
Puupponen-Pimiä R, Seppänen-Laakso T, Kankainen M, Maukonen J, Törrönen R, Kolehmainen M, Leppänen T, Moilanen E, Nohynek L, Aura AM, Poutanen K, Tómas-Barberán FA, Espín JC, Oksman-Caldentey KM. Puupponen-Pimiä R, et al. Mol Nutr Food Res. 2013 Dec;57(12):2258-63. doi: 10.1002/mnfr.201300280. Epub 2013 Aug 12. Mol Nutr Food Res. 2013. PMID: 23934737 Clinical Trial.
Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway.
Ritala A, Dong L, Imseng N, Seppänen-Laakso T, Vasilev N, van der Krol S, Rischer H, Maaheimo H, Virkki A, Brändli J, Schillberg S, Eibl R, Bouwmeester H, Oksman-Caldentey KM. Ritala A, et al. J Biotechnol. 2014 Apr 20;176:20-8. doi: 10.1016/j.jbiotec.2014.01.031. Epub 2014 Feb 14. J Biotechnol. 2014. PMID: 24530945
The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus.
Van Moerkercke A, Steensma P, Schweizer F, Pollier J, Gariboldi I, Payne R, Vanden Bossche R, Miettinen K, Espoz J, Purnama PC, Kellner F, Seppänen-Laakso T, O'Connor SE, Rischer H, Memelink J, Goossens A. Van Moerkercke A, et al. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8130-5. doi: 10.1073/pnas.1504951112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080427 Free PMC article.
93 results