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Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.
Aho V, Ollila HM, Kronholm E, Bondia-Pons I, Soininen P, Kangas AJ, Hilvo M, Seppälä I, Kettunen J, Oikonen M, Raitoharju E, Hyötyläinen T, Kähönen M, Viikari JS, Härmä M, Sallinen M, Olkkonen VM, Alenius H, Jauhiainen M, Paunio T, Lehtimäki T, Salomaa V, Orešič M, Raitakari OT, Ala-Korpela M, Porkka-Heiskanen T. Aho V, et al. Among authors: seppala i. Sci Rep. 2016 Apr 22;6:24828. doi: 10.1038/srep24828. Sci Rep. 2016. PMID: 27102866 Free PMC article.
Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque.
Fan YM, Hernesniemi J, Oksala N, Levula M, Raitoharju E, Collings A, Hutri-Kähönen N, Juonala M, Marniemi J, Lyytikäinen LP, Seppälä I, Mennander A, Tarkka M, Kangas AJ, Soininen P, Salenius JP, Klopp N, Illig T, Laitinen T, Ala-Korpela M, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Fan YM, et al. Among authors: seppala i. Sci Rep. 2014 Apr 11;4:4650. doi: 10.1038/srep04650. Sci Rep. 2014. PMID: 24722012 Free PMC article.
Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study.
Raitoharju E, Seppälä I, Oksala N, Lyytikäinen LP, Raitakari O, Viikari J, Ala-Korpela M, Soininen P, Kangas AJ, Waldenberger M, Klopp N, Illig T, Leiviskä J, Loo BM, Hutri-Kähönen N, Kähönen M, Laaksonen R, Lehtimäki T. Raitoharju E, et al. Among authors: seppala i. Mol Cell Endocrinol. 2014 Jun 25;391(1-2):41-9. doi: 10.1016/j.mce.2014.04.013. Epub 2014 Apr 28. Mol Cell Endocrinol. 2014. PMID: 24784704
Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism-The Young Finns Study.
Raitoharju E, Seppälä I, Lyytikäinen LP, Viikari J, Ala-Korpela M, Soininen P, Kangas AJ, Waldenberger M, Klopp N, Illig T, Leiviskä J, Loo BM, Oksala N, Kähönen M, Hutri-Kähönen N, Laaksonen R, Raitakari O, Lehtimäki T. Raitoharju E, et al. Among authors: seppala i. Sci Rep. 2016 Dec 5;6:38262. doi: 10.1038/srep38262. Sci Rep. 2016. PMID: 27917915 Free PMC article. Clinical Trial.
Fatty liver is associated with blood pathways of inflammatory response, immune system activation and prothrombotic state in Young Finns Study.
Taipale T, Seppälä I, Raitoharju E, Mononen N, Lyytikäinen LP, Illig T, Waldenberger M, Juonala M, Hutri-Kähönen N, Oksala N, Kähönen M, Raitakari O, Lehtimäki T. Taipale T, et al. Among authors: seppala i. Sci Rep. 2018 Jul 9;8(1):10358. doi: 10.1038/s41598-018-28563-y. Sci Rep. 2018. PMID: 29985430 Free PMC article.
Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health.
Marttila S, Rovio S, Mishra PP, Seppälä I, Lyytikäinen LP, Juonala M, Waldenberger M, Oksala N, Ala-Korpela M, Harville E, Hutri-Kähönen N, Kähönen M, Raitakari O, Lehtimäki T, Raitoharju E. Marttila S, et al. Among authors: seppala i. Sci Rep. 2021 Apr 28;11(1):9203. doi: 10.1038/s41598-021-88465-4. Sci Rep. 2021. PMID: 33911114 Free PMC article.
Activated immune-inflammatory pathways are associated with long-standing depressive symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study.
Elovainio M, Taipale T, Seppälä I, Mononen N, Raitoharju E, Jokela M, Pulkki-Råback L, Illig T, Waldenberger M, Hakulinen C, Hintsa T, Kivimäki M, Kähönen M, Keltikangas-Järvinen L, Raitakari O, Lehtimäki T. Elovainio M, et al. Among authors: seppala i. J Psychiatr Res. 2015 Dec;71:120-5. doi: 10.1016/j.jpsychires.2015.09.017. Epub 2015 Oct 22. J Psychiatr Res. 2015. PMID: 26473696
Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study.
Sulkava M, Raitoharju E, Levula M, Seppälä I, Lyytikäinen LP, Mennander A, Järvinen O, Zeitlin R, Salenius JP, Illig T, Klopp N, Mononen N, Laaksonen R, Kähönen M, Oksala N, Lehtimäki T. Sulkava M, et al. Among authors: seppala i. Sci Rep. 2017 Jan 27;7:41483. doi: 10.1038/srep41483. Sci Rep. 2017. PMID: 28128285 Free PMC article.
240 results