Seong J - Search Results

1

Discovery of β-Arrestin Biased Ligands of 5-HT₇R.

Kim Y, Kim H, Lee J, Lee JK, Min SJ, Seong J, Rhim H, Tae J, Lee HJ, Choo H. Kim Y, et al. Among authors: seong j. J Med Chem. 2018 Aug 23;61(16):7218-7233. doi: 10.1021/acs.jmedchem.8b00642. Epub 2018 Aug 1. J Med Chem. 2018. PMID: 30028132

2

In silico probing and biological evaluation of SETDB1/ESET-targeted novel compounds that reduce tri-methylated histone H3K9 (H3K9me3) level.

Park I, Hwang YJ, Kim T, Viswanath ANI, Londhe AM, Jung SY, Sim KM, Min SJ, Lee JE, Seong J, Kim YK, No KT, Ryu H, Pae AN. Park I, et al. Among authors: seong j. J Comput Aided Mol Des. 2017 Oct;31(10):877-889. doi: 10.1007/s10822-017-0052-3. Epub 2017 Sep 6. J Comput Aided Mol Des. 2017. PMID: 28879500

3

Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's disease.

Lim JW, Kim SK, Choi SY, Kim DH, Gadhe CG, Lee HN, Kim HJ, Kim J, Cho SJ, Hwang H, Seong J, Jeong KS, Lee JY, Lim SM, Lee JW, Pae AN. Lim JW, et al. Among authors: seong j. Eur J Med Chem. 2018 Sep 5;157:405-422. doi: 10.1016/j.ejmech.2018.07.071. Epub 2018 Aug 3. Eur J Med Chem. 2018. PMID: 30103190

4

Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model.

Hwang YJ, Hyeon SJ, Kim Y, Lim S, Lee MY, Kim J, Londhe AM, Gotina L, Kim Y, Pae AN, Cho YS, Seong J, Seo H, Kim YK, Choo H, Ryu H, Min SJ. Hwang YJ, et al. Among authors: seong j. J Enzyme Inhib Med Chem. 2021 Dec;36(1):856-868. doi: 10.1080/14756366.2021.1900160. J Enzyme Inhib Med Chem. 2021. PMID: 33771089 Free PMC article.

5

Pharmacophore-based virtual screening, biological evaluation and binding mode analysis of a novel protease-activated receptor 2 antagonist.

Cho NC, Seo SH, Kim D, Shin JS, Ju J, Seong J, Seo SH, Lee I, Lee KT, Kim YK, No KT, Pae AN. Cho NC, et al. Among authors: seong j. J Comput Aided Mol Des. 2016 Aug;30(8):625-37. doi: 10.1007/s10822-016-9937-9. Epub 2016 Sep 6. J Comput Aided Mol Des. 2016. PMID: 27600555

6

Spatiotemporal Characterization of GPCR Activity and Function during Endosomal Trafficking Pathway.

Kim H, Lee HN, Choi J, Seong J. Kim H, et al. Among authors: seong j. Anal Chem. 2021 Feb 2;93(4):2010-2017. doi: 10.1021/acs.analchem.0c03323. Epub 2021 Jan 5. Anal Chem. 2021. PMID: 33400862

7

FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains.

Seong J, Huang M, Sim KM, Kim H, Wang Y. Seong J, et al. Sci Rep. 2017 May 9;7(1):1593. doi: 10.1038/s41598-017-01789-y. Sci Rep. 2017. PMID: 28487538 Free PMC article.

8

Visualization of differential GPCR crosstalk in DRD1-DRD2 heterodimer upon different dopamine levels.

Kim H, Nam MH, Jeong S, Lee H, Oh SJ, Kim J, Choi N, Seong J. Kim H, et al. Among authors: seong j. Prog Neurobiol. 2022 Jun;213:102266. doi: 10.1016/j.pneurobio.2022.102266. Epub 2022 Mar 29. Prog Neurobiol. 2022. PMID: 35364139 Free article.

9

Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism.

Lee HN, Sim KM, Kim H, Ju J, Pae AN, Park JB, Ryu H, Seong J. Lee HN, et al. Among authors: seong j. Sci Rep. 2019 Oct 29;9(1):15557. doi: 10.1038/s41598-019-51914-2. Sci Rep. 2019. PMID: 31664099 Free PMC article.

10

Genetically encoded fluorescent biosensors for GPCR research.

Kim H, Baek IY, Seong J. Kim H, et al. Among authors: seong j. Front Cell Dev Biol. 2022 Sep 29;10:1007893. doi: 10.3389/fcell.2022.1007893. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36247000 Free PMC article. Review.

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