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The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.
Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H. Tsuda M, et al. Among authors: seno h. J Clin Invest. 2018 Aug 1;128(8):3475-3489. doi: 10.1172/JCI94287. Epub 2018 Jul 16. J Clin Invest. 2018. PMID: 30010625 Free PMC article.
ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H. Kimura Y, et al. Among authors: seno h. Gastroenterology. 2018 Jul;155(1):194-209.e2. doi: 10.1053/j.gastro.2018.03.039. Epub 2018 Mar 29. Gastroenterology. 2018. PMID: 29604291
Arid1a is essential for intestinal stem cells through Sox9 regulation.
Hiramatsu Y, Fukuda A, Ogawa S, Goto N, Ikuta K, Tsuda M, Matsumoto Y, Kimura Y, Yoshioka T, Takada Y, Maruno T, Hanyu Y, Tsuruyama T, Wang Z, Akiyama H, Takaishi S, Miyoshi H, Taketo MM, Chiba T, Seno H. Hiramatsu Y, et al. Among authors: seno h. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1704-1713. doi: 10.1073/pnas.1804858116. Epub 2019 Jan 11. Proc Natl Acad Sci U S A. 2019. PMID: 30635419 Free PMC article.
Bmi1 marks gastric stem cells located in the isthmus in mice.
Yoshioka T, Fukuda A, Araki O, Ogawa S, Hanyu Y, Matsumoto Y, Yamaga Y, Nakanishi Y, Kawada K, Sakai Y, Chiba T, Seno H. Yoshioka T, et al. Among authors: seno h. J Pathol. 2019 Jun;248(2):179-190. doi: 10.1002/path.5244. Epub 2019 Feb 20. J Pathol. 2019. PMID: 30689202
Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
Nishikawa Y, Kodama Y, Shiokawa M, Matsumori T, Marui S, Kuriyama K, Kuwada T, Sogabe Y, Kakiuchi N, Tomono T, Mima A, Morita T, Ueda T, Tsuda M, Yamauchi Y, Sakuma Y, Ota Y, Maruno T, Uza N, Uesugi M, Kageyama R, Chiba T, Seno H. Nishikawa Y, et al. Among authors: seno h. Oncogene. 2019 May;38(22):4283-4296. doi: 10.1038/s41388-019-0718-5. Epub 2019 Jan 31. Oncogene. 2019. PMID: 30705405
Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells.
Goto N, Fukuda A, Yamaga Y, Yoshikawa T, Maruno T, Maekawa H, Inamoto S, Kawada K, Sakai Y, Miyoshi H, Taketo MM, Chiba T, Seno H. Goto N, et al. Among authors: seno h. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12996-13005. doi: 10.1073/pnas.1900251116. Epub 2019 Jun 10. Proc Natl Acad Sci U S A. 2019. PMID: 31182574 Free PMC article.
517 results