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Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice.
Zhang J, Sharma D, Dinabandhu A, Sanchez J, Applewhite B, Jee K, Deshpande M, Flores-Bellver M, Hu MW, Guo C, Salman S, Hwang Y, Anders NM, Rudek MA, Qian J, Canto-Soler MV, Semenza GL, Montaner S, Sodhi A. Zhang J, et al. Among authors: semenza gl. J Clin Invest. 2023 Jul 3;133(13):e163290. doi: 10.1172/JCI163290. J Clin Invest. 2023. PMID: 37227777 Free PMC article.
Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes.
Lyu Y, Yang Y, Talwar V, Lu H, Chen C, Salman S, Wicks EE, Huang TY, Drehmer D, Wang Y, Zuo Q, Datan E, Jackson W 3rd, Dordai D, Wang R, Semenza GL. Lyu Y, et al. Among authors: semenza gl. Cell Rep. 2024 Apr 23;43(4):113972. doi: 10.1016/j.celrep.2024.113972. Epub 2024 Mar 21. Cell Rep. 2024. PMID: 38517892 Free article.
Retraction Note: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs.
Zhang H, Wong CCL, Wei H, Gilkes DM, Korangath P, Chaturvedi P, Schito L, Chen J, Krishnamachary B, Winnard PT Jr, Raman V, Zhen L, Mitzner WA, Sukumar S, Semenza GL. Zhang H, et al. Among authors: semenza gl. Oncogene. 2023 Jul;42(28):2234. doi: 10.1038/s41388-023-02720-8. Oncogene. 2023. PMID: 37221224 Free PMC article. No abstract available.
446 results