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Anti-inflammatory activity of superoxide dismutase mimics functionalized with cell-penetrating peptides.
Mathieu E , Bernard AS , Ching HYV , Somogyi A , Medjoubi K , Fores JR , Bertrand HC , Vincent A , Trépout S , Guerquin-Kern JL , Scheitler A , Ivanović-Burmazović I , Seksik P , Delsuc N , Policar C . Mathieu E , et al. Among authors: seksik p. Dalton Trans. 2020 Feb 21;49(7):2323-2330. doi: 10.1039/c9dt04619d. Epub 2020 Feb 5. Dalton Trans. 2020. PMID: 32022053
A Cell-Penetrant Manganese Superoxide Dismutase (MnSOD) Mimic Is Able To Complement MnSOD and Exerts an Antiinflammatory Effect on Cellular and Animal Models of Inflammatory Bowel Diseases.
Mathieu E, Bernard AS, Delsuc N, Quévrain E, Gazzah G, Lai B, Chain F, Langella P, Bachelet M, Masliah J, Seksik P, Policar C. Mathieu E, et al. Among authors: seksik p. Inorg Chem. 2017 Mar 6;56(5):2545-2555. doi: 10.1021/acs.inorgchem.6b02695. Epub 2017 Feb 15. Inorg Chem. 2017. PMID: 28198622
An easy-to-implement combinatorial approach involving an activity-based assay for the discovery of a peptidyl copper complex mimicking superoxide dismutase.
Vincent A , Fores JR , Tauziet E , Quévrain E , Dancs Á , Conte-Daban A , Bernard AS , Pelupessy P , Coulibaly K , Seksik P , Hureau C , Selmeczi K , Policar C , Delsuc N . Vincent A , et al. Among authors: seksik p. Chem Commun (Camb). 2020 Jan 2;56(3):399-402. doi: 10.1039/c9cc07920c. Chem Commun (Camb). 2020. PMID: 31820751
Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese(ii) superoxide dismutase mimic complex.
Mathieu E , Bernard AS , Quévrain E , Zoumpoulaki M , Iriart S , Lung-Soong C , Lai B , Medjoubi K , Henry L , Nagarajan S , Poyer F , Scheitler A , Ivanović-Burmazović I , Marco S , Somogyi A , Seksik P , Delsuc N , Policar C . Mathieu E , et al. Among authors: seksik p. Chem Commun (Camb). 2020 Jul 21;56(57):7885-7888. doi: 10.1039/d0cc03398g. Epub 2020 Jun 10. Chem Commun (Camb). 2020. PMID: 32520039 Free article.
Inertness of Superoxide Dismutase Mimics Mn(II) Complexes Based on an Open-Chain Ligand, Bioactivity, and Detection in Intestinal Epithelial Cells.
Schanne G, Zoumpoulaki M, Gazzah G, Vincent A, Preud'homme H, Lobinski R, Demignot S, Seksik P, Delsuc N, Policar C. Schanne G, et al. Among authors: seksik p. Oxid Med Cell Longev. 2022 Apr 1;2022:3858122. doi: 10.1155/2022/3858122. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35401918 Free PMC article.
Deciphering the Metal Speciation in Low-Molecular-Weight Complexes by IMS-MS: Application to the Detection of Manganese Superoxide Dismutase Mimics in Cell Lysates.
Zoumpoulaki M, Schanne G, Delsuc N, Preud'homme H, Quévrain E, Eskenazi N, Gazzah G, Guillot R, Seksik P, Vinh J, Lobinski R, Policar C. Zoumpoulaki M, et al. Among authors: seksik p. Angew Chem Int Ed Engl. 2022 Sep 19;61(38):e202203066. doi: 10.1002/anie.202203066. Epub 2022 Jul 4. Angew Chem Int Ed Engl. 2022. PMID: 35672261
Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota.
Landman C, Grill JP, Mallet JM, Marteau P, Humbert L, Le Balc'h E, Maubert MA, Perez K, Chaara W, Brot L, Beaugerie L, Sokol H, Thenet S, Rainteau D, Seksik P, Quévrain E; Saint Antoine IBD Network. Landman C, et al. Among authors: seksik p. PLoS One. 2018 Aug 29;13(8):e0202587. doi: 10.1371/journal.pone.0202587. eCollection 2018. PLoS One. 2018. PMID: 30157234 Free PMC article.
Nancy Index Scores of Chronic Inflammatory Bowel Disease Activity Associate With Development of Colorectal Neoplasia.
Kirchgesner J, Svrcek M, Le Gall G, Landman C, Dray X, Bourrier A, Nion-Larmurier I, Hoyeau N, Sokol H, Seksik P, Cosnes J, Fléjou JF, Beaugerie L; Saint-Antoine Inflammatory Bowel Disease Network. Kirchgesner J, et al. Among authors: seksik p. Clin Gastroenterol Hepatol. 2020 Jan;18(1):150-157.e1. doi: 10.1016/j.cgh.2019.05.002. Epub 2019 May 11. Clin Gastroenterol Hepatol. 2020. PMID: 31085339 Free article.
227 results