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Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition.
Catalano A, Adlesic M, Kaltenbacher T, Klar RFU, Albers J, Seidel P, Brandt LP, Hejhal T, Busenhart P, Röhner N, Zodel K, Fritsch K, Wild PJ, Duyster J, Fritsch R, Brummer T, Frew IJ. Catalano A, et al. Among authors: seidel p. Cancers (Basel). 2021 Apr 13;13(8):1852. doi: 10.3390/cancers13081852. Cancers (Basel). 2021. PMID: 33924486 Free PMC article.
HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Hoefflin R, Harlander S, Schäfer S, Metzger P, Kuo F, Schönenberger D, Adlesic M, Peighambari A, Seidel P, Chen CY, Consenza-Contreras M, Jud A, Lahrmann B, Grabe N, Heide D, Uhl FM, Chan TA, Duyster J, Zeiser R, Schell C, Heikenwalder M, Schilling O, Hakimi AA, Boerries M, Frew IJ. Hoefflin R, et al. Among authors: seidel p. Nat Commun. 2020 Aug 17;11(1):4111. doi: 10.1038/s41467-020-17873-3. Nat Commun. 2020. PMID: 32807776 Free PMC article.
Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma.
Hoefflin R, Harlander S, Abhari BA, Peighambari A, Adlesic M, Seidel P, Zodel K, Haug S, Göcmen B, Li Y, Lahrmann B, Grabe N, Heide D, Boerries M, Köttgen A, Heikenwalder M, Frew IJ. Hoefflin R, et al. Among authors: seidel p. Cancers (Basel). 2021 Sep 25;13(19):4801. doi: 10.3390/cancers13194801. Cancers (Basel). 2021. PMID: 34638286 Free PMC article.
ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.
Seidel P, Rubarth A, Zodel K, Peighambari A, Neumann F, Federkiel Y, Huang H, Hoefflin R, Adlesic M, Witt C, Hoffmann DJ, Metzger P, Lindemann RK, Zenke FT, Schell C, Boerries M, von Elverfeldt D, Reichardt W, Follo M, Albers J, Frew IJ. Seidel P, et al. JCI Insight. 2022 Dec 22;7(24):e156087. doi: 10.1172/jci.insight.156087. JCI Insight. 2022. PMID: 36413415 Free PMC article.
Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche.
Chiblak S, Tang Z, Lemke D, Knoll M, Dokic I, Warta R, Moustafa M, Mier W, Brons S, Rapp C, Muschal S, Seidel P, Bendszus M, Adeberg S, Wiestler OD, Haberkorn U, Debus J, Herold-Mende C, Wick W, Abdollahi A. Chiblak S, et al. Among authors: seidel p. JCI Insight. 2019 Jan 24;4(2):e123837. doi: 10.1172/jci.insight.123837. JCI Insight. 2019. PMID: 30674721 Free PMC article.
Radioresistance and Transcriptional Reprograming of Invasive Glioblastoma Cells.
Tang Z, Dokic I, Knoll M, Ciamarone F, Schwager C, Klein C, Cebulla G, Hoffmann DC, Schlegel J, Seidel P, Rutenberg C, Brons S, Herold-Mende C, Wick W, Debus J, Lemke D, Abdollahi A. Tang Z, et al. Among authors: seidel p. Int J Radiat Oncol Biol Phys. 2022 Feb 1;112(2):499-513. doi: 10.1016/j.ijrobp.2021.09.017. Epub 2021 Sep 14. Int J Radiat Oncol Biol Phys. 2022. PMID: 34534627 Free article.
Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling.
Felcht M, Luck R, Schering A, Seidel P, Srivastava K, Hu J, Bartol A, Kienast Y, Vettel C, Loos EK, Kutschera S, Bartels S, Appak S, Besemfelder E, Terhardt D, Chavakis E, Wieland T, Klein C, Thomas M, Uemura A, Goerdt S, Augustin HG. Felcht M, et al. Among authors: seidel p. J Clin Invest. 2012 Jun;122(6):1991-2005. doi: 10.1172/JCI58832. Epub 2012 May 15. J Clin Invest. 2012. PMID: 22585576 Free PMC article.
101 results