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The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia.
Verbeke D, Demeyer S, Prieto C, de Bock CE, De Bie J, Gielen O, Jacobs K, Mentens N, Verhoeven BM, Uyttebroeck A, Boeckx N, De Keersmaecker K, Maertens J, Segers H, Cools J. Verbeke D, et al. Among authors: segers h. Clin Cancer Res. 2020 Nov 1;26(21):5747-5758. doi: 10.1158/1078-0432.CCR-20-1315. Epub 2020 Aug 21. Clin Cancer Res. 2020. PMID: 32826328
PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.
Govaerts I, Prieto C, Vandersmissen C, Gielen O, Jacobs K, Provost S, Nittner D, Maertens J, Boeckx N, De Keersmaecker K, Segers H, Cools J. Govaerts I, et al. Among authors: segers h. J Hematol Oncol. 2021 Jun 24;14(1):97. doi: 10.1186/s13045-021-01114-1. J Hematol Oncol. 2021. PMID: 34167562 Free PMC article.
Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing.
Meyers S, Alberti-Servera L, Gielen O, Erard M, Swings T, De Bie J, Michaux L, Dewaele B, Boeckx N, Uyttebroeck A, De Keersmaecker K, Maertens J, Segers H, Cools J, Demeyer S. Meyers S, et al. Among authors: segers h. Hemasphere. 2022 Mar 10;6(4):e700. doi: 10.1097/HS9.0000000000000700. eCollection 2022 Apr. Hemasphere. 2022. PMID: 35291210 Free PMC article.
Randomized controlled trial on the effect of 1-hour infusion of vincristine versus push injection on neuropathy in children with cancer (final analysis).
Uittenboogaard A, van den Berg MH, Abbink FCH, Twisk JWR, van der Sluis IM, van den Bos C, van den Heuvel-Eibrink MM, Segers H, Chantrain C, van der Werff Ten Bosch J, Willems L, Kaspers GJL, van de Velde ME. Uittenboogaard A, et al. Among authors: segers h. Cancer Med. 2023 Oct;12(19):19480-19490. doi: 10.1002/cam4.6550. Epub 2023 Sep 21. Cancer Med. 2023. PMID: 37732486 Free PMC article. Clinical Trial.
57 results