Sefkow M - Search Results

1

Targeting G Protein-Coupled Receptors by Capture Compound Mass Spectrometry: A Case Study with Sertindole.

Blex C, Michaelis S, Schrey AK, Furkert J, Eichhorst J, Bartho K, Gyapon Quast F, Marais A, Hakelberg M, Gruber U, Niquet S, Popp O, Kroll F, Sefkow M, Schülein R, Dreger M, Köster H. Blex C, et al. Among authors: sefkow m. Chembiochem. 2017 Aug 17;18(16):1639-1649. doi: 10.1002/cbic.201700152. Epub 2017 Jul 7. Chembiochem. 2017. PMID: 28557180

2

Identification of Potential Off-target Toxicity Liabilities of Catechol-O-methyltransferase Inhibitors by Differential Competition Capture Compound Mass Spectrometry.

von Kleist L, Michaelis S, Bartho K, Graebner O, Schlief M, Dreger M, Schrey AK, Sefkow M, Kroll F, Koester H, Luo Y. von Kleist L, et al. Among authors: sefkow m. J Med Chem. 2016 May 26;59(10):4664-75. doi: 10.1021/acs.jmedchem.5b01970. Epub 2016 Apr 25. J Med Chem. 2016. PMID: 27074629

3

The cAMP capture compound mass spectrometry as a novel tool for targeting cAMP-binding proteins: from protein kinase A to potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channels.

Luo Y, Blex C, Baessler O, Glinski M, Dreger M, Sefkow M, Köster H. Luo Y, et al. Among authors: sefkow m. Mol Cell Proteomics. 2009 Dec;8(12):2843-56. doi: 10.1074/mcp.M900110-MCP200. Epub 2009 Sep 9. Mol Cell Proteomics. 2009. PMID: 19741253 Free PMC article.

4

GDP-capture compound--a novel tool for the profiling of GTPases in pro- and eukaryotes by capture compound mass spectrometry (CCMS).

Luo Y, Fischer JJ, Baessler OY, Schrey AK, Ungewiss J, Glinski M, Sefkow M, Dreger M, Koester H. Luo Y, et al. Among authors: sefkow m. J Proteomics. 2010 Feb 10;73(4):815-9. doi: 10.1016/j.jprot.2009.12.002. Epub 2009 Dec 21. J Proteomics. 2010. PMID: 20026263

5

Comprehensive identification of staurosporine-binding kinases in the hepatocyte cell line HepG2 using Capture Compound Mass Spectrometry (CCMS).

Fischer JJ, Graebner Baessler OY, Dalhoff C, Michaelis S, Schrey AK, Ungewiss J, Andrich K, Jeske D, Kroll F, Glinski M, Sefkow M, Dreger M, Koester H. Fischer JJ, et al. Among authors: sefkow m. J Proteome Res. 2010 Feb 5;9(2):806-17. doi: 10.1021/pr9007333. J Proteome Res. 2010. PMID: 20028079

6

Dabigatran and dabigatran ethyl ester: potent inhibitors of ribosyldihydronicotinamide dehydrogenase (NQO2).

Michaelis S, Marais A, Schrey AK, Graebner OY, Schaudt C, Sefkow M, Kroll F, Dreger M, Glinski M, Koester H, Metternich R, Fischer JJ. Michaelis S, et al. Among authors: sefkow m. J Med Chem. 2012 Apr 26;55(8):3934-44. doi: 10.1021/jm3001339. Epub 2012 Apr 17. J Med Chem. 2012. PMID: 22494098

7

Dasatinib, imatinib and staurosporine capture compounds - Complementary tools for the profiling of kinases by Capture Compound Mass Spectrometry (CCMS).

Fischer JJ, Dalhoff C, Schrey AK, Graebner OY, Michaelis S, Andrich K, Glinski M, Kroll F, Sefkow M, Dreger M, Koester H. Fischer JJ, et al. Among authors: sefkow m. J Proteomics. 2011 Dec 10;75(1):160-8. doi: 10.1016/j.jprot.2011.05.035. Epub 2011 Jun 2. J Proteomics. 2011. PMID: 21664307

8

Using S-adenosyl-L-homocysteine capture compounds to characterize S-adenosyl-L-methionine and S-adenosyl-L-homocysteine binding proteins.

Brown LJ, Baranowski M, Wang Y, Schrey AK, Lenz T, Taverna SD, Cole PA, Sefkow M. Brown LJ, et al. Among authors: sefkow m. Anal Biochem. 2014 Dec 15;467:14-21. doi: 10.1016/j.ab.2014.08.013. Epub 2014 Aug 27. Anal Biochem. 2014. PMID: 25172130 Free PMC article.

9

A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma.

Joosten M, Ginzel S, Blex C, Schmidt D, Gombert M, Chen C, Linka RM, Gräbner O, Hain A, Hirsch B, Sommerfeld A, Seegebarth A, Gruber U, Maneck C, Zhang L, Stenin K, Dieks H, Sefkow M, Münk C, Baldus CD, Thiele R, Borkhardt A, Hummel M, Köster H, Fischer U, Dreger M, Seitz V. Joosten M, et al. Among authors: sefkow m. Mol Oncol. 2016 Oct;10(8):1232-44. doi: 10.1016/j.molonc.2016.06.001. Epub 2016 Jun 9. Mol Oncol. 2016. PMID: 27324824 Free PMC article.

10

Bridged bicyclic peptides as potential drug scaffolds: synthesis, structure, protein binding and stability.

Bartoloni M, Jin X, Marcaida MJ, Banha J, Dibonaventura I, Bongoni S, Bartho K, Gräbner O, Sefkow M, Darbre T, Reymond JL. Bartoloni M, et al. Among authors: sefkow m. Chem Sci. 2015 Oct 1;6(10):5473-5490. doi: 10.1039/c5sc01699a. Epub 2015 Jul 13. Chem Sci. 2015. PMID: 29861888 Free PMC article.

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