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LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation.
Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez RS, Taguchi T, De Cecco M, Leonova KI, Kogan V, Helfand SL, Neretti N, Roichman A, Cohen HY, Meer MV, Gladyshev VN, Antoch MP, Gudkov AV, Sedivy JM, Seluanov A, Gorbunova V. Simon M, et al. Among authors: sedivy jm. Cell Metab. 2019 Apr 2;29(4):871-885.e5. doi: 10.1016/j.cmet.2019.02.014. Epub 2019 Mar 7. Cell Metab. 2019. PMID: 30853213 Free PMC article.
Death by transposition - the enemy within?
Sedivy JM, Kreiling JA, Neretti N, De Cecco M, Criscione SW, Hofmann JW, Zhao X, Ito T, Peterson AL. Sedivy JM, et al. Bioessays. 2013 Dec;35(12):1035-43. doi: 10.1002/bies.201300097. Epub 2013 Oct 15. Bioessays. 2013. PMID: 24129940 Free PMC article.
Human Genomics. Sleeping dogs of the genome.
Gorbunova V, Boeke JD, Helfand SL, Sedivy JM. Gorbunova V, et al. Among authors: sedivy jm. Science. 2014 Dec 5;346(6214):1187-8. doi: 10.1126/science.aaa3177. Science. 2014. PMID: 25477445 Free PMC article. No abstract available.
Reduced expression of MYC increases longevity and enhances healthspan.
Hofmann JW, Zhao X, De Cecco M, Peterson AL, Pagliaroli L, Manivannan J, Hubbard GB, Ikeno Y, Zhang Y, Feng B, Li X, Serre T, Qi W, Van Remmen H, Miller RA, Bath KG, de Cabo R, Xu H, Neretti N, Sedivy JM. Hofmann JW, et al. Among authors: sedivy jm. Cell. 2015 Jan 29;160(3):477-88. doi: 10.1016/j.cell.2014.12.016. Epub 2015 Jan 22. Cell. 2015. PMID: 25619689 Free PMC article.
165 results