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VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface.
Hesketh GG, Pérez-Dorado I, Jackson LP, Wartosch L, Schäfer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MNJ, Luzio JP, Owen DJ. Hesketh GG, et al. Among authors: seaman mnj. Dev Cell. 2014 Jun 9;29(5):591-606. doi: 10.1016/j.devcel.2014.04.010. Epub 2014 May 22. Dev Cell. 2014. PMID: 24856514 Free PMC article.
Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.
Crawley-Snowdon H, Yang JC, Zaccai NR, Davis LJ, Wartosch L, Herman EK, Bright NA, Swarbrick JS, Collins BM, Jackson LP, Seaman MNJ, Luzio JP, Dacks JB, Neuhaus D, Owen DJ. Crawley-Snowdon H, et al. Among authors: seaman mnj. Nat Commun. 2020 Oct 6;11(1):5031. doi: 10.1038/s41467-020-18773-2. Nat Commun. 2020. PMID: 33024112 Free PMC article.
71 results