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Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma.
Meyer SN, Scuoppo C, Vlasevska S, Bal E, Holmes AB, Holloman M, Garcia-Ibanez L, Nataraj S, Duval R, Vantrimpont T, Basso K, Brooks N, Dalla-Favera R, Pasqualucci L. Meyer SN, et al. Among authors: scuoppo c. Immunity. 2019 Sep 17;51(3):535-547.e9. doi: 10.1016/j.immuni.2019.08.006. Epub 2019 Sep 10. Immunity. 2019. PMID: 31519498 Free PMC article.
Repurposing dasatinib for diffuse large B cell lymphoma.
Scuoppo C, Wang J, Persaud M, Mittan SK, Basso K, Pasqualucci L, Rabadan R, Inghirami G, Grandori C, Bosch F, Dalla-Favera R. Scuoppo C, et al. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16981-16986. doi: 10.1073/pnas.1905239116. Epub 2019 Aug 5. Proc Natl Acad Sci U S A. 2019. PMID: 31383760 Free PMC article.
Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.
Fabbri G, Holmes AB, Viganotti M, Scuoppo C, Belver L, Herranz D, Yan XJ, Kieso Y, Rossi D, Gaidano G, Chiorazzi N, Ferrando AA, Dalla-Favera R. Fabbri G, et al. Among authors: scuoppo c. Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2911-E2919. doi: 10.1073/pnas.1702564114. Epub 2017 Mar 17. Proc Natl Acad Sci U S A. 2017. PMID: 28314854 Free PMC article.
Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity.
Marsilio S, Khiabanian H, Fabbri G, Vergani S, Scuoppo C, Montserrat E, Shpall EJ, Hadigol M, Marin P, Rai KR, Rabadan R, Devereux S, Pasqualucci L, Chiorazzi N. Marsilio S, et al. Among authors: scuoppo c. Leukemia. 2018 Apr;32(4):1041-1044. doi: 10.1038/leu.2017.343. Epub 2017 Dec 5. Leukemia. 2018. PMID: 29203856 Free PMC article. No abstract available.
A common functional consequence of tumor-derived mutations within c-MYC.
Chakraborty AA, Scuoppo C, Dey S, Thomas LR, Lorey SL, Lowe SW, Tansey WP. Chakraborty AA, et al. Among authors: scuoppo c. Oncogene. 2015 Apr 30;34(18):2406-9. doi: 10.1038/onc.2014.186. Epub 2014 Jul 7. Oncogene. 2015. PMID: 24998853 Free PMC article.
A tumour suppressor network relying on the polyamine-hypusine axis.
Scuoppo C, Miething C, Lindqvist L, Reyes J, Ruse C, Appelmann I, Yoon S, Krasnitz A, Teruya-Feldstein J, Pappin D, Pelletier J, Lowe SW. Scuoppo C, et al. Nature. 2012 Jul 12;487(7406):244-8. doi: 10.1038/nature11126. Nature. 2012. PMID: 22722845 Free PMC article.
Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.
Liu Y, Chen C, Xu Z, Scuoppo C, Rillahan CD, Gao J, Spitzer B, Bosbach B, Kastenhuber ER, Baslan T, Ackermann S, Cheng L, Wang Q, Niu T, Schultz N, Levine RL, Mills AA, Lowe SW. Liu Y, et al. Among authors: scuoppo c. Nature. 2016 Mar 24;531(7595):471-475. doi: 10.1038/nature17157. Epub 2016 Mar 16. Nature. 2016. PMID: 26982726 Free PMC article.
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