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Functionally diverse type V CRISPR-Cas systems.
Yan WX, Hunnewell P, Alfonse LE, Carte JM, Keston-Smith E, Sothiselvam S, Garrity AJ, Chong S, Makarova KS, Koonin EV, Cheng DR, Scott DA. Yan WX, et al. Among authors: scott da. Science. 2019 Jan 4;363(6422):88-91. doi: 10.1126/science.aav7271. Epub 2018 Dec 6. Science. 2019. PMID: 30523077
Genome-scale CRISPR-Cas9 knockout screening in human cells.
Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelson T, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Shalem O, et al. Among authors: scott da. Science. 2014 Jan 3;343(6166):84-87. doi: 10.1126/science.1247005. Epub 2013 Dec 12. Science. 2014. PMID: 24336571 Free PMC article.
In vivo genome editing using Staphylococcus aureus Cas9.
Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. Ran FA, et al. Among authors: scott da. Nature. 2015 Apr 9;520(7546):186-91. doi: 10.1038/nature14299. Epub 2015 Apr 1. Nature. 2015. PMID: 25830891 Free PMC article.
Rationally engineered Cas9 nucleases with improved specificity.
Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Slaymaker IM, et al. Among authors: scott da. Science. 2016 Jan 1;351(6268):84-8. doi: 10.1126/science.aad5227. Epub 2015 Dec 1. Science. 2016. PMID: 26628643 Free PMC article.
Diversity and evolution of class 2 CRISPR-Cas systems.
Shmakov S, Smargon A, Scott D, Cox D, Pyzocha N, Yan W, Abudayyeh OO, Gootenberg JS, Makarova KS, Wolf YI, Severinov K, Zhang F, Koonin EV. Shmakov S, et al. Nat Rev Microbiol. 2017 Mar;15(3):169-182. doi: 10.1038/nrmicro.2016.184. Epub 2017 Jan 23. Nat Rev Microbiol. 2017. PMID: 28111461 Free PMC article.
CRISPR-Cas in mobile genetic elements: counter-defence and beyond.
Faure G, Shmakov SA, Yan WX, Cheng DR, Scott DA, Peters JE, Makarova KS, Koonin EV. Faure G, et al. Among authors: scott da. Nat Rev Microbiol. 2019 Aug;17(8):513-525. doi: 10.1038/s41579-019-0204-7. Nat Rev Microbiol. 2019. PMID: 31165781
Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
Makarova KS, Wolf YI, Iranzo J, Shmakov SA, Alkhnbashi OS, Brouns SJJ, Charpentier E, Cheng D, Haft DH, Horvath P, Moineau S, Mojica FJM, Scott D, Shah SA, Siksnys V, Terns MP, Venclovas Č, White MF, Yakunin AF, Yan W, Zhang F, Garrett RA, Backofen R, van der Oost J, Barrangou R, Koonin EV. Makarova KS, et al. Nat Rev Microbiol. 2020 Feb;18(2):67-83. doi: 10.1038/s41579-019-0299-x. Epub 2019 Dec 19. Nat Rev Microbiol. 2020. PMID: 31857715 Free PMC article. Review.
Structure of the type V-C CRISPR-Cas effector enzyme.
Kurihara N, Nakagawa R, Hirano H, Okazaki S, Tomita A, Kobayashi K, Kusakizako T, Nishizawa T, Yamashita K, Scott DA, Nishimasu H, Nureki O. Kurihara N, et al. Among authors: scott da. Mol Cell. 2022 May 19;82(10):1865-1877.e4. doi: 10.1016/j.molcel.2022.03.006. Epub 2022 Apr 1. Mol Cell. 2022. PMID: 35366394 Free PMC article.
879 results