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eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation.
Schmidt T, Dabrowska A, Waldron JA, Hodge K, Koulouras G, Gabrielsen M, Munro J, Tack DC, Harris G, McGhee E, Scott D, Carlin LM, Huang D, Le Quesne J, Zanivan S, Wilczynska A, Bushell M. Schmidt T, et al. Among authors: scott d. Nucleic Acids Res. 2023 Feb 28;51(4):1859-1879. doi: 10.1093/nar/gkad030. Nucleic Acids Res. 2023. PMID: 36727461 Free PMC article.
Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement.
Vankemmelbeke M, McIntosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG. Vankemmelbeke M, et al. Among authors: scott d. Cancer Res. 2020 Aug 15;80(16):3399-3412. doi: 10.1158/0008-5472.CAN-19-3599. Epub 2020 Jun 12. Cancer Res. 2020. PMID: 32532823 Free PMC article.
The adaptability of the ion-binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF.
Lithgo RM, Hanževački M, Harris G, Kamps JJAG, Holden E, Gianga TM, Benesch JLP, Jäger CM, Croft AK, Hussain R, Hobman JL, Orville AM, Quigley A, Carr SB, Scott DJ. Lithgo RM, et al. J Biol Chem. 2023 Nov;299(11):105331. doi: 10.1016/j.jbc.2023.105331. Epub 2023 Oct 14. J Biol Chem. 2023. PMID: 37820867 Free PMC article.
Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis.
Calver JF, Parmar NR, Harris G, Lithgo RM, Stylianou P, Zetterberg FR, Gooptu B, Mackinnon AC, Carr SB, Borthwick LA, Scott DJ, Stewart ID, Slack RJ, Jenkins RG, John AE. Calver JF, et al. Among authors: scott dj. J Biol Chem. 2024 Apr 17:107300. doi: 10.1016/j.jbc.2024.107300. Online ahead of print. J Biol Chem. 2024. PMID: 38641066 Free article.
6,521 results