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A broadly protective antibody that targets the flavivirus NS1 protein.
Modhiran N, Song H, Liu L, Bletchly C, Brillault L, Amarilla AA, Xu X, Qi J, Chai Y, Cheung STM, Traves R, Setoh YX, Bibby S, Scott CAP, Freney ME, Newton ND, Khromykh AA, Chappell KJ, Muller DA, Stacey KJ, Landsberg MJ, Shi Y, Gao GF, Young PR, Watterson D. Modhiran N, et al. Among authors: scott cap. Science. 2021 Jan 8;371(6525):190-194. doi: 10.1126/science.abb9425. Science. 2021. PMID: 33414219
Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2.
Watterson D, Wijesundara DK, Modhiran N, Mordant FL, Li Z, Avumegah MS, McMillan CL, Lackenby J, Guilfoyle K, van Amerongen G, Stittelaar K, Cheung ST, Bibby S, Daleris M, Hoger K, Gillard M, Radunz E, Jones ML, Hughes K, Hughes B, Goh J, Edwards D, Scoble J, Pearce L, Kowalczyk L, Phan T, La M, Lu L, Pham T, Zhou Q, Brockman DA, Morgan SJ, Lau C, Tran MH, Tapley P, Villalón-Letelier F, Barnes J, Young A, Jaberolansar N, Scott CA, Isaacs A, Amarilla AA, Khromykh AA, van den Brand JM, Reading PC, Ranasinghe C, Subbarao K, Munro TP, Young PR, Chappell KJ. Watterson D, et al. Clin Transl Immunology. 2021 Apr 5;10(4):e1269. doi: 10.1002/cti2.1269. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33841880 Free PMC article.
A platform technology for generating subunit vaccines against diverse viral pathogens.
Young A, Isaacs A, Scott CAP, Modhiran N, McMillan CLD, Cheung STM, Barr J, Marsh G, Thakur N, Bailey D, Li KSM, Luk HKH, Kok KH, Lau SKP, Woo PCY, Furuyama W, Marzi A, Young PR, Chappell KJ, Watterson D. Young A, et al. Among authors: scott cap. Front Immunol. 2022 Aug 18;13:963023. doi: 10.3389/fimmu.2022.963023. eCollection 2022. Front Immunol. 2022. PMID: 36059532 Free PMC article.
Structure and antigenicity of divergent Henipavirus fusion glycoproteins.
Isaacs A, Low YS, Macauslane KL, Seitanidou J, Pegg CL, Cheung STM, Liang B, Scott CAP, Landsberg MJ, Schulz BL, Chappell KJ, Modhiran N, Watterson D. Isaacs A, et al. Among authors: scott cap. Nat Commun. 2023 Jun 16;14(1):3577. doi: 10.1038/s41467-023-39278-8. Nat Commun. 2023. PMID: 37328468 Free PMC article.