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Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals.
Tobe R, Carlson BA, Huh JH, Castro NP, Xu XM, Tsuji PA, Lee SG, Bang J, Na JW, Kong YY, Beaglehole D, Southon E, Seifried H, Tessarollo L, Salomon DS, Schweizer U, Gladyshev VN, Hatfield DL, Lee BJ. Tobe R, et al. Among authors: schweizer u. Biochem J. 2016 Jul 15;473(14):2141-54. doi: 10.1042/BCJ20160393. Epub 2016 May 16. Biochem J. 2016. PMID: 27208177 Free PMC article.
Selective restoration of the selenoprotein population in a mouse hepatocyte selenoproteinless background with different mutant selenocysteine tRNAs lacking Um34.
Carlson BA, Moustafa ME, Sengupta A, Schweizer U, Shrimali R, Rao M, Zhong N, Wang S, Feigenbaum L, Lee BJ, Gladyshev VN, Hatfield DL. Carlson BA, et al. Among authors: schweizer u. J Biol Chem. 2007 Nov 9;282(45):32591-602. doi: 10.1074/jbc.M707036200. Epub 2007 Sep 11. J Biol Chem. 2007. PMID: 17848557 Free article.
The selenocysteine tRNA STAF-binding region is essential for adequate selenocysteine tRNA status, selenoprotein expression and early age survival of mice.
Carlson BA, Schweizer U, Perella C, Shrimali RK, Feigenbaum L, Shen L, Speransky S, Floss T, Jeong SJ, Watts J, Hoffmann V, Combs GF, Gladyshev VN, Hatfield DL. Carlson BA, et al. Among authors: schweizer u. Biochem J. 2009 Feb 15;418(1):61-71. doi: 10.1042/BJ20081304. Biochem J. 2009. PMID: 18973473 Free PMC article.
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration.
Wirth EK, Conrad M, Winterer J, Wozny C, Carlson BA, Roth S, Schmitz D, Bornkamm GW, Coppola V, Tessarollo L, Schomburg L, Köhrle J, Hatfield DL, Schweizer U. Wirth EK, et al. Among authors: schweizer u. FASEB J. 2010 Mar;24(3):844-52. doi: 10.1096/fj.09-143974. Epub 2009 Nov 4. FASEB J. 2010. PMID: 19890015 Free PMC article.
., Tessarollo, L., Schomburg, L., Kohrle, J., Hatfield, D. L., Schweizer, U. Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration....
., Tessarollo, L., Schomburg, L., Kohrle, J., Hatfield, D. L., Schweizer, U. Neuronal selenoprotein expression is required for …
Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice.
Kasaikina MV, Fomenko DE, Labunskyy VM, Lachke SA, Qiu W, Moncaster JA, Zhang J, Wojnarowicz MW Jr, Natarajan SK, Malinouski M, Schweizer U, Tsuji PA, Carlson BA, Maas RL, Lou MF, Goldstein LE, Hatfield DL, Gladyshev VN. Kasaikina MV, et al. Among authors: schweizer u. J Biol Chem. 2011 Sep 23;286(38):33203-12. doi: 10.1074/jbc.M111.259218. Epub 2011 Jul 18. J Biol Chem. 2011. PMID: 21768092 Free PMC article.
134 results