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The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice.
Lappe-Siefke C, Loebrich S, Hevers W, Waidmann OB, Schweizer M, Fehr S, Fritschy JM, Dikic I, Eilers J, Wilson SM, Kneussel M. Lappe-Siefke C, et al. Among authors: schweizer m. PLoS Genet. 2009 Sep;5(9):e1000631. doi: 10.1371/journal.pgen.1000631. Epub 2009 Sep 4. PLoS Genet. 2009. PMID: 19759851 Free PMC article.
Neuroligin 1 is dynamically exchanged at postsynaptic sites.
Schapitz IU, Behrend B, Pechmann Y, Lappe-Siefke C, Kneussel SJ, Wallace KE, Stempel AV, Buck F, Grant SG, Schweizer M, Schmitz D, Schwarz JR, Holzbaur EL, Kneussel M. Schapitz IU, et al. Among authors: schweizer m. J Neurosci. 2010 Sep 22;30(38):12733-44. doi: 10.1523/JNEUROSCI.0896-10.2010. J Neurosci. 2010. PMID: 20861378 Free PMC article.
The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory.
Muhia M, Thies E, Labonté D, Ghiretti AE, Gromova KV, Xompero F, Lappe-Siefke C, Hermans-Borgmeyer I, Kuhl D, Schweizer M, Ohana O, Schwarz JR, Holzbaur ELF, Kneussel M. Muhia M, et al. Among authors: schweizer m. Cell Rep. 2016 May 3;15(5):968-977. doi: 10.1016/j.celrep.2016.03.086. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117409 Free PMC article.
SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals.
Andres-Alonso M, Ammar MR, Butnaru I, Gomes GM, Acuña Sanhueza G, Raman R, Yuanxiang P, Borgmeyer M, Lopez-Rojas J, Raza SA, Brice N, Hausrat TJ, Macharadze T, Diaz-Gonzalez S, Carlton M, Failla AV, Stork O, Schweizer M, Gundelfinger ED, Kneussel M, Spilker C, Karpova A, Kreutz MR. Andres-Alonso M, et al. Among authors: schweizer m. Nat Commun. 2019 Nov 29;10(1):5448. doi: 10.1038/s41467-019-13224-z. Nat Commun. 2019. PMID: 31784514 Free PMC article.
Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits.
Lopes AT, Hausrat TJ, Heisler FF, Gromova KV, Lombino FL, Fischer T, Ruschkies L, Breiden P, Thies E, Hermans-Borgmeyer I, Schweizer M, Schwarz JR, Lohr C, Kneussel M. Lopes AT, et al. Among authors: schweizer m. PLoS Biol. 2020 Aug 31;18(8):e3000820. doi: 10.1371/journal.pbio.3000820. eCollection 2020 Aug. PLoS Biol. 2020. PMID: 32866173 Free PMC article.
759 results