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Page 1
The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function.
Nitz K, Lacy M, Bianchini M, Wichapong K, Kücükgöze IA, Bonfiglio CA, Migheli R, Wu Y, Burger C, Li Y, Forné I, Ammar C, Janjic A, Mohanta S, Duchene J, Heemskerk JWM, Megens RTA, Schwedhelm E, Huveneers S, Lygate CA, Santovito D, Zimmer R, Imhof A, Weber C, Lutgens E, Atzler D. Nitz K, et al. Among authors: schwedhelm e. Circ Res. 2022 Sep 30;131(8):701-712. doi: 10.1161/CIRCRESAHA.122.321094. Epub 2022 Sep 14. Circ Res. 2022. PMID: 36102188
Extensive characterization of the human DDAH1 transgenic mice.
Schwedhelm E, von Leitner EC, Atzler D, Schmitz C, Jacobi J, Meinertz T, Münzel T, Baldus S, Cooke JP, Böger RH, Maas R, Sydow K. Schwedhelm E, et al. Pharmacol Res. 2009 Dec;60(6):494-502. doi: 10.1016/j.phrs.2009.08.001. Epub 2009 Aug 8. Pharmacol Res. 2009. PMID: 19666120
Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1-deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine.
Hu X, Xu X, Zhu G, Atzler D, Kimoto M, Chen J, Schwedhelm E, Lüneburg N, Böger RH, Zhang P, Chen Y. Hu X, et al. Among authors: schwedhelm e. Circulation. 2009 Dec 1;120(22):2222-9. doi: 10.1161/CIRCULATIONAHA.108.819912. Epub 2009 Nov 16. Circulation. 2009. PMID: 19917889 Free PMC article.
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
von Leitner EC, Klinke A, Atzler D, Slocum JL, Lund N, Kielstein JT, Maas R, Schmidt-Haupt R, Pekarova M, Hellwinkel O, Tsikas D, D'Alecy LG, Lau D, Willems S, Kubala L, Ehmke H, Meinertz T, Blankenberg S, Schwedhelm E, Gadegbeku CA, Böger RH, Baldus S, Sydow K. von Leitner EC, et al. Among authors: schwedhelm e. Circulation. 2011 Dec 13;124(24):2735-45. doi: 10.1161/CIRCULATIONAHA.111.060541. Epub 2011 Nov 14. Circulation. 2011. PMID: 22082678
Homoarginine--an independent marker of mortality in heart failure.
Atzler D, Rosenberg M, Anderssohn M, Choe CU, Lutz M, Zugck C, Böger RH, Frey N, Schwedhelm E. Atzler D, et al. Among authors: schwedhelm e. Int J Cardiol. 2013 Oct 12;168(5):4907-9. doi: 10.1016/j.ijcard.2013.07.099. Epub 2013 Jul 24. Int J Cardiol. 2013. PMID: 23890923 No abstract available.
Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies.
Choe CU, Atzler D, Wild PS, Carter AM, Böger RH, Ojeda F, Simova O, Stockebrand M, Lackner K, Nabuurs C, Marescau B, Streichert T, Müller C, Lüneburg N, De Deyn PP, Benndorf RA, Baldus S, Gerloff C, Blankenberg S, Heerschap A, Grant PJ, Magnus T, Zeller T, Isbrandt D, Schwedhelm E. Choe CU, et al. Among authors: schwedhelm e. Circulation. 2013 Sep 24;128(13):1451-61. doi: 10.1161/CIRCULATIONAHA.112.000580. Epub 2013 Sep 4. Circulation. 2013. PMID: 24004504
248 results