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Dendritic cell therapy with CD137L-DC-EBV-VAX in locally recurrent or metastatic nasopharyngeal carcinoma is safe and confers clinical benefit.
Nickles E, Dharmadhikari B, Yating L, Walsh RJ, Koh LP, Poon M, Tan LK, Wang LZ, Ang Y, Asokumaran Y, Chong WQ, Huang Y, Loh KS, Tay J, Soo R, Koh M, Ho LP, Chan M, Niam M, Soh M, Luah YH, Lim CM, Kaliaperumal N, Au VB, Talib NBSN, Sng R, Connolly JE, Goh BC, Schwarz H. Nickles E, et al. Among authors: schwarz h. Cancer Immunol Immunother. 2022 Jun;71(6):1531-1543. doi: 10.1007/s00262-021-03075-3. Epub 2021 Oct 18. Cancer Immunol Immunother. 2022. PMID: 34661709 Free PMC article. Clinical Trial.
Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors.
Prasad M, Ponnalagu S, Zeng Q, Luu K, Lang SM, Wong HY, Cheng MS, Wu M, Mallilankaraman K, Sobota RM, Lim YT, Wang LC, Goh CK, Tay KXJ, Loh KS, Wang CI, Lee WH, Goh BC, Lim CM, Schwarz H. Prasad M, et al. Among authors: schwarz h. Cancer Immunol Immunother. 2022 Nov;71(11):2583-2596. doi: 10.1007/s00262-022-03183-8. Epub 2022 Mar 17. Cancer Immunol Immunother. 2022. PMID: 35299256 Free PMC article.
Hiding in Plain Sight: Soluble Immunomodulatory Receptors.
Dahal LN, Schwarz H, Ward FJ. Dahal LN, et al. Among authors: schwarz h. Trends Immunol. 2018 Oct;39(10):771-774. doi: 10.1016/j.it.2018.08.004. Epub 2018 Sep 5. Trends Immunol. 2018. PMID: 30195467
1,371 results