Schwartz DM - Search Results

1

Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology.

Schwartz DM, Farley TK, Richoz N, Yao C, Shih HY, Petermann F, Zhang Y, Sun HW, Hayes E, Mikami Y, Jiang K, Davis FP, Kanno Y, Milner JD, Siegel R, Laurence A, Meylan F, O'Shea JJ. Schwartz DM, et al. Immunity. 2019 Jan 15;50(1):106-120.e10. doi: 10.1016/j.immuni.2018.12.014. Immunity. 2019. PMID: 30650370 Free PMC article.

2

The JAK-STAT pathway: impact on human disease and therapeutic intervention.

O'Shea JJ, Schwartz DM, Villarino AV, Gadina M, McInnes IB, Laurence A. O'Shea JJ, et al. Among authors: schwartz dm. Annu Rev Med. 2015;66:311-28. doi: 10.1146/annurev-med-051113-024537. Annu Rev Med. 2015. PMID: 25587654 Free PMC article. Review.

3

Decernotinib: A Next-Generation Jakinib.

Gadina M, Schwartz DM, O'Shea JJ. Gadina M, et al. Among authors: schwartz dm. Arthritis Rheumatol. 2016 Jan;68(1):31-4. doi: 10.1002/art.39463. Arthritis Rheumatol. 2016. PMID: 26479275 Free PMC article. No abstract available.

4

Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases.

Schwartz DM, Bonelli M, Gadina M, O'Shea JJ. Schwartz DM, et al. Nat Rev Rheumatol. 2016 Jan;12(1):25-36. doi: 10.1038/nrrheum.2015.167. Epub 2015 Dec 3. Nat Rev Rheumatol. 2016. PMID: 26633291 Free PMC article. Review.

5

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease.

Zhou Q, Wang H, Schwartz DM, Stoffels M, Park YH, Zhang Y, Yang D, Demirkaya E, Takeuchi M, Tsai WL, Lyons JJ, Yu X, Ouyang C, Chen C, Chin DT, Zaal K, Chandrasekharappa SC, Hanson EP, Yu Z, Mullikin JC, Hasni SA, Wertz IE, Ombrello AK, Stone DL, Hoffmann P, Jones A, Barham BK, Leavis HL, van Royen-Kerkof A, Sibley C, Batu ED, Gül A, Siegel RM, Boehm M, Milner JD, Ozen S, Gadina M, Chae J, Laxer RM, Kastner DL, Aksentijevich I. Zhou Q, et al. Among authors: schwartz dm. Nat Genet. 2016 Jan;48(1):67-73. doi: 10.1038/ng.3459. Epub 2015 Dec 7. Nat Genet. 2016. PMID: 26642243 Free PMC article.

6

Targeting cytokine signaling in autoimmunity: back to the future and beyond.

Hirahara K, Schwartz D, Gadina M, Kanno Y, O'Shea JJ. Hirahara K, et al. Curr Opin Immunol. 2016 Dec;43:89-97. doi: 10.1016/j.coi.2016.10.001. Epub 2016 Nov 4. Curr Opin Immunol. 2016. PMID: 27821272 Review.

7

JAK inhibition as a therapeutic strategy for immune and inflammatory diseases.

Schwartz DM, Kanno Y, Villarino A, Ward M, Gadina M, O'Shea JJ. Schwartz DM, et al. Nat Rev Drug Discov. 2017 Dec;16(12):843-862. doi: 10.1038/nrd.2017.201. Epub 2017 Nov 6. Nat Rev Drug Discov. 2017. PMID: 29104284 Review.

8

JAK inhibition as a therapeutic strategy for immune and inflammatory diseases.

Schwartz DM, Kanno Y, Villarino A, Ward M, Gadina M, O'Shea JJ. Schwartz DM, et al. Nat Rev Drug Discov. 2017 Dec 28;17(1):78. doi: 10.1038/nrd.2017.267. Nat Rev Drug Discov. 2017. PMID: 29282366 Free PMC article.

9

Translational and clinical advances in JAK-STAT biology: The present and future of jakinibs.

Gadina M, Johnson C, Schwartz D, Bonelli M, Hasni S, Kanno Y, Changelian P, Laurence A, O'Shea JJ. Gadina M, et al. J Leukoc Biol. 2018 Sep;104(3):499-514. doi: 10.1002/JLB.5RI0218-084R. Epub 2018 Jul 12. J Leukoc Biol. 2018. PMID: 29999544 Review.

10

Janus kinases to jakinibs: from basic insights to clinical practice.

Gadina M, Le MT, Schwartz DM, Silvennoinen O, Nakayamada S, Yamaoka K, O'Shea JJ. Gadina M, et al. Among authors: schwartz dm. Rheumatology (Oxford). 2019 Feb 1;58(Suppl 1):i4-i16. doi: 10.1093/rheumatology/key432. Rheumatology (Oxford). 2019. PMID: 30806710 Free PMC article. Review.

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