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The cephalic phase of insulin release is modulated by IL-1β.
Wiedemann SJ, Trimigliozzi K, Dror E, Meier DT, Molina-Tijeras JA, Rachid L, Le Foll C, Magnan C, Schulze F, Stawiski M, Häuselmann SP, Méreau H, Böni-Schnetzler M, Donath MY. Wiedemann SJ, et al. Among authors: schulze f. Cell Metab. 2022 Jul 5;34(7):991-1003.e6. doi: 10.1016/j.cmet.2022.06.001. Epub 2022 Jun 23. Cell Metab. 2022. PMID: 35750050 Free article.
Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.
Dror E, Dalmas E, Meier DT, Wueest S, Thévenet J, Thienel C, Timper K, Nordmann TM, Traub S, Schulze F, Item F, Vallois D, Pattou F, Kerr-Conte J, Lavallard V, Berney T, Thorens B, Konrad D, Böni-Schnetzler M, Donath MY. Dror E, et al. Among authors: schulze f. Nat Immunol. 2017 Mar;18(3):283-292. doi: 10.1038/ni.3659. Epub 2017 Jan 16. Nat Immunol. 2017. PMID: 28092375 Free article.
The Role of Inflammation in β-cell Dedifferentiation.
Nordmann TM, Dror E, Schulze F, Traub S, Berishvili E, Barbieux C, Böni-Schnetzler M, Donath MY. Nordmann TM, et al. Among authors: schulze f. Sci Rep. 2017 Jul 24;7(1):6285. doi: 10.1038/s41598-017-06731-w. Sci Rep. 2017. PMID: 28740254 Free PMC article.
Inhibition of IL-1beta improves Glycaemia in a Mouse Model for Gestational Diabetes.
Schulze F, Wehner J, Kratschmar DV, Makshana V, Meier DT, Häuselmann SP, Dalmas E, Thienel C, Dror E, Wiedemann SJ, Traub S, Nordmann TM, Rachid L, De Baat A, Rohm TV, Zhao C, Odermatt A, Böni-Schnetzler M, Donath MY. Schulze F, et al. Sci Rep. 2020 Feb 20;10(1):3035. doi: 10.1038/s41598-020-59701-0. Sci Rep. 2020. PMID: 32080229 Free PMC article.
IL-1beta promotes the age-associated decline of beta cell function.
Böni-Schnetzler M, Méreau H, Rachid L, Wiedemann SJ, Schulze F, Trimigliozzi K, Meier DT, Donath MY. Böni-Schnetzler M, et al. Among authors: schulze f. iScience. 2021 Oct 9;24(11):103250. doi: 10.1016/j.isci.2021.103250. eCollection 2021 Nov 19. iScience. 2021. PMID: 34746709 Free PMC article.
255 results